{"id":"W2116725410","doi":"10.4049/jimmunol.173.7.4500","title":"Critical Role of TNF Receptor Type-2 (p75) as a Costimulator for IL-2 Induction and T Cell Survival: A Functional Link to CD28","year":2004,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":106,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"National Cancer Institute; Michael Smith Health Research BC","keywords":"CD28; T-cell receptor; Cell biology; T cell; Biology; ZAP70; Phosphorylation; Intracellular; Signal transduction; Immunology; Immune system","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005532739,0.0001361823,0.0003090299,0.0001887081,0.0001708758,0.000009284873,0.0001523002,0.0002497577,0.0005831652],"category_scores_gemma":[0.0006966416,0.00009979717,0.0001030797,0.0001324577,0.0002297815,0.0001490291,0.00005415831,0.000484078,0.0002181436],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007703189,"about_ca_system_score_gemma":0.0001447743,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005986198,"about_ca_topic_score_gemma":0.00000369557,"domain_scores_codex":[0.9988954,0.0002200705,0.000500145,0.000116669,0.00004938124,0.000218306],"domain_scores_gemma":[0.9983878,0.0004856963,0.0002771026,0.000162052,0.000662043,0.00002530885],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.005649523,0.0001551124,0.00004855849,0.00001020159,0.0002062909,3.573031e-7,0.0005947576,0.00008441016,0.9856778,0.001936943,0.002118364,0.003517684],"study_design_scores_gemma":[0.004503569,0.007179111,0.00629543,0.00008832396,0.0002307614,0.001108852,0.003254245,0.000003761814,0.758628,0.002832188,0.2156576,0.000218183],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9786327,0.004836778,0.001993309,0.004666124,0.009209879,0.0002426851,0.00000700327,0.00001669527,0.000394854],"genre_scores_gemma":[0.9976028,0.0003220442,0.0002118474,0.0002859496,0.0001631861,0.000005122658,0.00001388427,0.0000177995,0.00137743],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2270498,"threshold_uncertainty_score":0.638525,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01559981787585466,"score_gpt":0.2582289071500452,"score_spread":0.2426290892741906,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}