{"id":"W2116725410","doi":"10.4049/jimmunol.173.7.4500","title":"Critical Role of TNF Receptor Type-2 (p75) as a Costimulator for IL-2 Induction and T Cell Survival: A Functional Link to CD28","year":2004,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":106,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"National Cancer Institute; Michael Smith Health Research BC","keywords":"CD28; T-cell receptor; Cell biology; T cell; Biology; ZAP70; Phosphorylation; Intracellular; Signal transduction; Immunology; Immune system","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000129065,0.0005516956,0.0001350492,0.0002619175,0.0002646105,0.0005657626,0.0001892081,0.0002715101,0.0005429015],"category_scores_gemma":[0.0001326917,0.00008370603,0.000129866,0.00009522821,0.0003628339,0.0003447399,0.0001908203,0.0002894634,0.0001868453],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005222067,"about_ca_system_score_gemma":0.0004694531,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007500087,"about_ca_topic_score_gemma":0.0008316459,"domain_scores_codex":[0.9998693,0.00001961932,0.0000102826,0.00002231703,0.00004050237,0.00003790366],"domain_scores_gemma":[0.9999129,0.00001062075,0.00002403897,0.000006383017,0.00001192618,0.00003409267],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002051342,0.00001647073,0.0003680494,0.00003542466,0.000003270849,0.000385139,0.00001625535,0.0001593847,0.9955524,0.0005583905,0.00004468455,0.002655432],"study_design_scores_gemma":[0.00004385804,0.0004265171,0.01190492,0.00001562051,0.00002197178,0.001794745,0.00007873267,0.002552771,0.9783763,0.0005598906,0.004215967,0.000008725969],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.984349,0.008949552,0.003652707,0.0002928129,0.00005089838,0.0000228254,0.0001110693,0.00007203628,0.002499053],"genre_scores_gemma":[0.9963459,0.001472673,0.00118915,0.00002381112,0.0000281096,0.00001025907,0.00005295298,0.000003617813,0.0008734197],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007500087,"threshold_uncertainty_score":0.003788948,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01559981787585466,"score_gpt":0.2582289071500452,"score_spread":0.2426290892741906,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}