{"id":"W2116757585","doi":"10.1016/j.abb.2015.10.012","title":"Combined effect of G3139 and TSPO ligands on Ca2+-induced permeability transition in rat brain mitochondria","year":2015,"lang":"en","type":"article","venue":"Archives of Biochemistry and Biophysics","topic":"Mitochondrial Function and Pathology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":26,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University; McGill University Health Centre","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; Canadian Institutes of Health Research; Russian Foundation for Basic Research; Canada Research Chairs; National Institute on Alcohol Abuse and Alcoholism; Deutsche Forschungsgemeinschaft","keywords":"Mitochondrial permeability transition pore; Mitochondrion; Chemistry; Permeability (electromagnetism); Biophysics; Transition (genetics); Biochemistry; Biology; Membrane","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001352303,0.0001610506,0.0002587776,0.00003394353,0.0000235037,0.000005245402,0.00007436848,0.0001410111,0.000001419957],"category_scores_gemma":[0.0001368443,0.0001414792,0.00006997635,0.00007008018,0.0002291051,0.000003679201,0.00004439723,0.0001012053,3.170412e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000003433272,"about_ca_system_score_gemma":0.00003976041,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001845229,"about_ca_topic_score_gemma":0.000003953794,"domain_scores_codex":[0.999167,0.00009145352,0.0002134385,0.0003204414,0.00007872277,0.0001289404],"domain_scores_gemma":[0.9994667,0.0000982262,0.00008376498,0.0002321406,0.000024871,0.00009436141],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002072089,0.0001069777,0.001996733,0.0001567426,0.00001714761,0.00000172339,0.0002739015,0.000004733364,0.9934238,0.00004394275,0.00007208252,0.001830174],"study_design_scores_gemma":[0.002148018,0.002194387,0.00106888,0.00004795827,0.00001603164,0.000006329972,0.0000850309,0.00007045039,0.9938365,0.0003361196,0.0000584092,0.0001318676],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9988779,0.00009040422,0.00007710129,0.0002170515,0.0001016695,0.0001657003,0.00003346554,0.000004707357,0.0004319602],"genre_scores_gemma":[0.9994287,0.0000428841,0.0001458868,0.00007355762,0.00009487331,0.000008918936,0.0001349657,0.000008324003,0.00006183684],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002087409,"threshold_uncertainty_score":0.5769355,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008661735628966988,"score_gpt":0.2383912973243264,"score_spread":0.2297295616953594,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}