{"id":"W2116788917","doi":"10.1128/iai.73.3.1275-1283.2005","title":"<i>Vibrio parahaemolyticus</i> Disruption of Epithelial Cell Tight Junctions Occurs Independently of Toxin Production","year":2005,"lang":"en","type":"article","venue":"Infection and Immunity","topic":"Vibrio bacteria research studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":69,"is_retracted":false,"has_abstract":true,"ca_institutions":"Canadian Food Inspection Agency; Health Sciences Centre; University of Calgary","funders":"Fondation pour la Recherche Médicale; Natural Sciences and Engineering Research Council of Canada; Canadian Food Inspection Agency","keywords":"Vibrio parahaemolyticus; Tight junction; Paracellular transport; Biology; Toxin; Occludin; Hemolysin; Virulence; Microbiology; Cholera toxin; Vibrio cholerae; Pneumolysin; Barrier function; Bacteria; Cell biology; Permeability (electromagnetism); Biochemistry; Gene; Membrane","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002202255,0.00009511298,0.0001276444,0.00007043681,0.0001132927,0.000009694239,0.00004758026,0.00008603178,0.00002101469],"category_scores_gemma":[0.0001157038,0.00008847949,0.00006030994,0.0001063769,0.0001594736,0.00001857422,0.00008941914,0.0001109442,0.000004518483],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001794146,"about_ca_system_score_gemma":0.00004020008,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002714617,"about_ca_topic_score_gemma":0.0002413806,"domain_scores_codex":[0.9993056,0.0001073099,0.0002095758,0.0001514259,0.0001079322,0.0001181656],"domain_scores_gemma":[0.9994619,0.000008144038,0.0001215043,0.0002168662,0.0001554286,0.00003617879],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001119616,0.0002095093,0.009763159,0.00004460066,0.00003733971,6.541951e-8,0.0001079486,0.0000445865,0.9844891,0.0000101717,0.000396923,0.004784668],"study_design_scores_gemma":[0.0004256502,0.000315868,0.1061262,0.00001245059,0.00002025834,0.000009304808,0.0000575917,0.00001416385,0.8799441,0.00001647969,0.01297494,0.00008303558],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9981026,0.0001988159,0.0003419006,0.0001240067,0.0002367596,0.0001714798,0.0000232225,0.000009946113,0.0007912423],"genre_scores_gemma":[0.9978674,0.001191108,0.0001010194,0.00001570348,0.0001502374,0.00001238479,0.00004756663,0.00000747573,0.0006070698],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.104545,"threshold_uncertainty_score":0.3608089,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01211459451018365,"score_gpt":0.2665710518418549,"score_spread":0.2544564573316712,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}