{"id":"W2116788917","doi":"10.1128/iai.73.3.1275-1283.2005","title":"<i>Vibrio parahaemolyticus</i> Disruption of Epithelial Cell Tight Junctions Occurs Independently of Toxin Production","year":2005,"lang":"en","type":"article","venue":"Infection and Immunity","topic":"Vibrio bacteria research studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":69,"is_retracted":false,"has_abstract":true,"ca_institutions":"Canadian Food Inspection Agency; Health Sciences Centre; University of Calgary","funders":"Fondation pour la Recherche Médicale; Natural Sciences and Engineering Research Council of Canada; Canadian Food Inspection Agency","keywords":"Vibrio parahaemolyticus; Tight junction; Paracellular transport; Biology; Toxin; Occludin; Hemolysin; Virulence; Microbiology; Cholera toxin; Vibrio cholerae; Pneumolysin; Barrier function; Bacteria; Cell biology; Permeability (electromagnetism); Biochemistry; Gene; Membrane","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002140761,0.0002844683,0.0002804034,0.0001464737,0.000139357,0.0005951963,0.0002058205,0.0003316073,0.0006045546],"category_scores_gemma":[0.0004727058,0.0001490727,0.0002623143,0.000176025,0.0003687483,0.0002702134,0.0002682989,0.0004314666,0.0003415014],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003630762,"about_ca_system_score_gemma":0.0002325161,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001836244,"about_ca_topic_score_gemma":0.001745004,"domain_scores_codex":[0.9994091,0.0001298628,0.00005659238,0.0001137417,0.0001685253,0.0001221329],"domain_scores_gemma":[0.9996707,0.00007051103,0.000118802,0.00004121432,0.00007534389,0.00002345353],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006131308,0.00002311063,0.001623761,0.0000503088,0.000005904903,0.00005943103,0.00001689625,0.00003407403,0.9974558,0.00004567298,0.00005082421,0.0005729094],"study_design_scores_gemma":[0.000006703563,0.0005065484,0.03104989,0.00001722646,0.00001617416,0.0006252927,0.00009450065,0.0004563906,0.96573,0.00005187872,0.001440193,0.000005261777],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9924054,0.001736333,0.003408975,0.0002720613,0.00003408486,0.00003993285,0.0005500039,0.00007858167,0.001474734],"genre_scores_gemma":[0.9958199,0.0005932791,0.002095384,0.0001360505,0.00001507966,0.0000243981,0.0006992079,0.00001584013,0.0006007378],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001836244,"threshold_uncertainty_score":0.003651083,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01211459451018365,"score_gpt":0.2665710518418549,"score_spread":0.2544564573316712,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}