{"id":"W2116811274","doi":"10.1093/intimm/dxh098","title":"A chimeric T cell receptor with super-signaling properties","year":2004,"lang":"en","type":"article","venue":"International Immunology","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":17,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Marsden Fund; Lotto New Zealand; Royal Society; Royal Society Te Apārangi; Wellcome Trust; McGill University","keywords":"T-cell receptor; CD3; Signal transduction; Cell biology; Biology; T cell; Antigen; Molecular biology; Autoimmunity; Chemistry; CD8; Immune system; Immunology","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001680367,0.0004287331,0.0002439214,0.0001628576,0.00008011772,0.0004162692,0.0003620528,0.0004839482,0.001393645],"category_scores_gemma":[0.0001586948,0.0001636065,0.0003389361,0.0001752292,0.0001717811,0.0002573642,0.0002422386,0.0008282954,0.00107439],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000339707,"about_ca_system_score_gemma":0.0001644267,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002659418,"about_ca_topic_score_gemma":0.0001751445,"domain_scores_codex":[0.9997771,0.00003649916,0.00001683461,0.00004964126,0.00006243832,0.0000574307],"domain_scores_gemma":[0.9998224,0.00003500711,0.0000427953,0.00003144452,0.00002433529,0.00004408367],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002220759,0.00000460832,0.00002985062,0.000007082446,0.000001601809,0.00003408885,0.000004014448,0.00005469715,0.9993317,0.0001071771,0.0000133585,0.0003897783],"study_design_scores_gemma":[0.0000279062,0.0002671788,0.001209359,0.000004790661,0.0000361114,0.001749893,0.00002082032,0.003335444,0.987257,0.0001136974,0.005968289,0.000009527548],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9741106,0.001360004,0.02135098,0.0001733546,0.00004667712,0.00004464305,0.000332158,0.0003013266,0.002280202],"genre_scores_gemma":[0.9879174,0.0005598192,0.00757154,0.0000778696,0.00001310463,0.00003494831,0.0005933323,0.00004627599,0.003185757],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001393645,"threshold_uncertainty_score":0.004662216,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01054180095819255,"score_gpt":0.1996783606594822,"score_spread":0.1891365597012896,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}