{"id":"W2116929194","doi":"10.1093/intimm/dxp085","title":"CD4 T cell cooperation is required for the in vivo activation of CD4 T cells","year":2009,"lang":"en","type":"article","venue":"International Immunology","topic":"T-cell and B-cell Immunology","field":"Immunology and Microbiology","cited_by":20,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Saskatchewan","funders":"Canadian Institutes of Health Research; University of Alberta","keywords":"T cell; CD40; Cell biology; Cytokine; Biology; Ovalbumin; Antigen-presenting cell; Population; Interleukin 21; Cytotoxic T cell; Immunology; Molecular biology; Chemistry; Immune system; In vitro; Biochemistry; Medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.000250993,0.0002007372,0.0002979685,0.0002464185,0.0001320223,0.00001558227,0.0006012144,0.0003942486,0.001024764],"category_scores_gemma":[0.00008440753,0.0001615757,0.0001289368,0.0001631638,0.0002627344,0.0001762287,0.00007088111,0.0003013455,0.0001501598],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00009149519,"about_ca_system_score_gemma":0.00007721692,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001946869,"about_ca_topic_score_gemma":0.0000242087,"domain_scores_codex":[0.9985797,0.0001316707,0.0005823068,0.0003266143,0.00004880743,0.0003308685],"domain_scores_gemma":[0.9986477,0.0004439917,0.0002966432,0.0003358077,0.000268277,0.000007594177],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006397127,0.0003457169,0.00009888125,0.000004651766,0.0001659555,0.000001042775,0.0005728676,0.00007069847,0.9836171,0.004580246,0.005886131,0.004016961],"study_design_scores_gemma":[0.002377777,0.0004214562,0.0007377771,0.00001947555,0.00002211039,0.00001703386,0.0002155763,0.0001123511,0.9197077,0.0008657312,0.0753556,0.0001473841],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9757306,0.002506936,0.003708484,0.008240778,0.003964724,0.000882549,0.0001195359,0.00006908605,0.004777302],"genre_scores_gemma":[0.9903802,0.0003479489,0.0001425939,0.0008997694,0.00005608137,0.00005976854,0.0001296211,0.00001414483,0.007969825],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.06946947,"threshold_uncertainty_score":0.9998884,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01392431555868829,"score_gpt":0.2491116202976082,"score_spread":0.2351873047389199,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}