{"id":"W2116929194","doi":"10.1093/intimm/dxp085","title":"CD4 T cell cooperation is required for the in vivo activation of CD4 T cells","year":2009,"lang":"en","type":"article","venue":"International Immunology","topic":"T-cell and B-cell Immunology","field":"Immunology and Microbiology","cited_by":20,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Saskatchewan","funders":"Canadian Institutes of Health Research; University of Alberta","keywords":"T cell; CD40; Cell biology; Cytokine; Biology; Ovalbumin; Antigen-presenting cell; Population; Interleukin 21; Cytotoxic T cell; Immunology; Molecular biology; Chemistry; Immune system; In vitro; Biochemistry; Medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000337312,0.000501669,0.0004332956,0.0001964425,0.0001743308,0.0004037367,0.0002137063,0.0004434669,0.002327877],"category_scores_gemma":[0.0002961101,0.0002150612,0.0002636334,0.00007868526,0.0001952531,0.000305046,0.0003547849,0.001078732,0.0009870694],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002225649,"about_ca_system_score_gemma":0.0002652447,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001736686,"about_ca_topic_score_gemma":0.000239956,"domain_scores_codex":[0.9995297,0.0001456118,0.00003044389,0.00007731687,0.00009517751,0.0001216916],"domain_scores_gemma":[0.9996647,0.00008397612,0.0000577946,0.00006022889,0.00003246488,0.0001009779],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001539572,0.00005831343,0.0003217008,0.00003025994,0.000004372973,0.00008645628,0.00001670201,0.0001027986,0.9977705,0.00009333304,0.00004414883,0.001317458],"study_design_scores_gemma":[0.0001373226,0.001518676,0.01106189,0.00002851476,0.00005131908,0.00148908,0.00008441251,0.003130259,0.973622,0.0004325225,0.008434689,0.000009439135],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9842696,0.002769152,0.007829777,0.0002829841,0.0001031407,0.0000540983,0.0001316724,0.0001876859,0.004371911],"genre_scores_gemma":[0.9940469,0.0004923627,0.002622236,0.00009197885,0.00005429915,0.00005603486,0.0002657793,0.00002962951,0.002340754],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002327877,"threshold_uncertainty_score":0.007787585,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01392431555868829,"score_gpt":0.2491116202976082,"score_spread":0.2351873047389199,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}