{"id":"W2116935659","doi":"10.1158/0008-5472.can-06-1769","title":"Estrogen Receptor Positive Breast Cancer Metastasis: Altered Hormonal Sensitivity and Tumor Aggressiveness in Lymphatic Vessels and Lymph Nodes","year":2006,"lang":"en","type":"article","venue":"Cancer Research","topic":"Cancer Cells and Metastasis","field":"Medicine","cited_by":135,"is_retracted":false,"has_abstract":true,"ca_institutions":"Immunovaccine (Canada)","funders":"Cancer Center, University of Colorado; National Cancer Institute; National Institutes of Health; Avon Foundation for Women; Breast Cancer Research Foundation; U.S. Department of Defense","keywords":"Estrogen receptor; Primary tumor; Lymphangiogenesis; Cancer research; Metastasis; Lymphatic system; Tumor microenvironment; Breast cancer; Lymph; Cancer; Estrogen; CD44; Pathology; Medicine; Biology; Internal medicine; Cell","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009608738,0.0002580207,0.0005773341,0.000336521,0.0001804543,0.0000919299,0.0000772889,0.00007680798,0.000189921],"category_scores_gemma":[0.00004737392,0.0002253284,0.00006777488,0.0005987005,0.0005029741,0.0001876911,0.0001498153,0.0002661692,0.00000587154],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006830776,"about_ca_system_score_gemma":0.0008696225,"about_ca_topic_candidate":true,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.02731705,"about_ca_topic_score_gemma":0.001170578,"domain_scores_codex":[0.9972585,0.0003872534,0.0003069881,0.0006650441,0.0006540074,0.0007281384],"domain_scores_gemma":[0.9987143,0.0002458341,0.00009488667,0.0002524336,0.0003933776,0.0002992277],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.003456399,0.0004565415,0.2936794,0.001054947,0.0004065548,0.0007918478,0.000549552,0.0000655717,0.5263556,0.0004551011,0.001129681,0.1715989],"study_design_scores_gemma":[0.005887842,0.0001273869,0.8406549,0.002039227,0.0002360616,0.0006173002,0.000593663,0.0002305557,0.1476268,0.0001845581,0.001337357,0.0004643473],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.96311,0.03280676,0.00001579855,0.00222743,0.0001086516,0.0005952548,0.000958579,0.00002163284,0.0001559318],"genre_scores_gemma":[0.9934141,0.005127643,0.0002017165,0.0001712856,0.0004378501,0.0003550189,0.00004075433,0.0000476029,0.0002040454],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.5469756,"threshold_uncertainty_score":0.9791601,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03449068499429694,"score_gpt":0.3561512617241167,"score_spread":0.3216605767298197,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}