{"id":"W2116935659","doi":"10.1158/0008-5472.can-06-1769","title":"Estrogen Receptor Positive Breast Cancer Metastasis: Altered Hormonal Sensitivity and Tumor Aggressiveness in Lymphatic Vessels and Lymph Nodes","year":2006,"lang":"en","type":"article","venue":"Cancer Research","topic":"Cancer Cells and Metastasis","field":"Medicine","cited_by":135,"is_retracted":false,"has_abstract":true,"ca_institutions":"Immunovaccine (Canada)","funders":"Cancer Center, University of Colorado; National Cancer Institute; National Institutes of Health; Avon Foundation for Women; Breast Cancer Research Foundation; U.S. Department of Defense","keywords":"Estrogen receptor; Primary tumor; Lymphangiogenesis; Cancer research; Metastasis; Lymphatic system; Tumor microenvironment; Breast cancer; Lymph; Cancer; Estrogen; CD44; Pathology; Medicine; Biology; Internal medicine; Cell","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001015731,0.0001381606,0.0001594483,0.0004773788,0.0001257941,0.0002404099,0.00007151286,0.0001533147,0.001802263],"category_scores_gemma":[0.00008117026,0.0000996743,0.0001080214,0.0002807629,0.0001327659,0.0001693127,0.0001276703,0.000213363,0.0002919507],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001866084,"about_ca_system_score_gemma":0.00008559183,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008212638,"about_ca_topic_score_gemma":0.001127256,"domain_scores_codex":[0.9999344,0.000007204079,0.000004013844,0.00001488528,0.00002177995,0.00001763522],"domain_scores_gemma":[0.9999416,0.000009172605,0.00001535787,0.000003925561,0.000008097706,0.00002181738],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001785758,0.00003597654,0.01127419,0.00004730601,0.00000918393,0.0002221795,0.00003031132,0.00003520654,0.983811,0.00008086681,0.0001072895,0.004167933],"study_design_scores_gemma":[0.00003414192,0.0005858138,0.5751111,0.00001808042,0.00006076879,0.005924419,0.0002261117,0.0008475892,0.4123384,0.0002293097,0.00460745,0.00001688165],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9953804,0.002487431,0.0006253992,0.00005774884,0.00000744648,0.000008263201,0.0002641655,0.00003176697,0.001137317],"genre_scores_gemma":[0.9958065,0.001081846,0.0003750872,0.00003660915,0.000008884595,0.00001156899,0.0003241735,0.000006298666,0.002349023],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001802263,"threshold_uncertainty_score":0.006029189,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03449068499429694,"score_gpt":0.3561512617241167,"score_spread":0.3216605767298197,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}