{"id":"W2116942623","doi":"10.15252/embj.201385965","title":"Insulators recruit histone methyltransferase dMes4 to regulate chromatin of flanking genes","year":2014,"lang":"en","type":"article","venue":"The EMBO Journal","topic":"Genomics and Chromatin Dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":44,"is_retracted":false,"has_abstract":false,"ca_institutions":"Simon Fraser University","funders":"NHLBI Division of Intramural Research; National Institute of Environmental Health Sciences; Natural Sciences and Engineering Research Council of Canada; National Institutes of Health; Canadian Institute for Advanced Research; Centre National de la Recherche Scientifique; Ligue Contre le Cancer; Institut National de la Santé et de la Recherche Médicale; Agence Nationale de la Recherche","keywords":"Biology; Chromatin; Nucleosome; Histone; Cell biology; Histone methyltransferase; Genetics; Histone code; Histone H3; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007462055,0.0001343921,0.0001826626,0.0000502013,0.0001561322,0.00002948837,0.000367595,0.00006761207,0.00003633445],"category_scores_gemma":[0.00006162733,0.00009814269,0.0001192225,0.00008278967,0.00005594275,0.000002707973,0.00007592223,0.0001270283,0.000008108088],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002234841,"about_ca_system_score_gemma":0.00005346256,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001400936,"about_ca_topic_score_gemma":0.00001985756,"domain_scores_codex":[0.9990174,0.0001294549,0.0003405132,0.0001484883,0.00015415,0.000209953],"domain_scores_gemma":[0.9992845,0.000018283,0.0001507636,0.0003546345,0.00008842125,0.0001033693],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004016619,0.00002284004,0.0002197882,0.0000145883,0.000065416,0.000001449493,0.0002781858,0.001998733,0.9847155,0.0002838825,0.0003868539,0.01197262],"study_design_scores_gemma":[0.001250425,0.0008386032,0.01058065,0.0001130221,0.000116417,0.000579408,0.0002177074,0.002876817,0.9463527,0.005155222,0.03139764,0.0005213611],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9890646,0.0006374777,0.008966616,0.0003822823,0.0002450958,0.0001024577,0.000005985683,0.000005117805,0.0005903271],"genre_scores_gemma":[0.9958436,0.0002049129,0.003069499,0.0002171376,0.0003420515,0.000003414653,0.000008257776,0.00002566829,0.0002854459],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03836275,"threshold_uncertainty_score":0.4002143,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00853818470029873,"score_gpt":0.2509937709002616,"score_spread":0.2424555861999629,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}