{"id":"W2116942623","doi":"10.15252/embj.201385965","title":"Insulators recruit histone methyltransferase dMes4 to regulate chromatin of flanking genes","year":2014,"lang":"en","type":"article","venue":"The EMBO Journal","topic":"Genomics and Chromatin Dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":44,"is_retracted":false,"has_abstract":false,"ca_institutions":"Simon Fraser University","funders":"NHLBI Division of Intramural Research; National Institute of Environmental Health Sciences; Natural Sciences and Engineering Research Council of Canada; National Institutes of Health; Canadian Institute for Advanced Research; Centre National de la Recherche Scientifique; Ligue Contre le Cancer; Institut National de la Santé et de la Recherche Médicale; Agence Nationale de la Recherche","keywords":"Biology; Chromatin; Nucleosome; Histone; Cell biology; Histone methyltransferase; Genetics; Histone code; Histone H3; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002324236,0.0002771903,0.0002404468,0.000358651,0.0002762535,0.0005673779,0.000456583,0.0002898012,0.003014988],"category_scores_gemma":[0.0003253353,0.0004655913,0.0003236885,0.0001864395,0.0003202647,0.000392664,0.000925105,0.0007044647,0.001712181],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007179162,"about_ca_system_score_gemma":0.0002279389,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008543061,"about_ca_topic_score_gemma":0.002180803,"domain_scores_codex":[0.9998048,0.0000162911,0.000006803029,0.00005084989,0.00006651844,0.00005481398],"domain_scores_gemma":[0.999813,0.00002817771,0.0000378394,0.00002915749,0.0000414389,0.0000503986],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001458688,0.00001198049,0.00170901,0.00001814809,0.000008883092,0.00004730302,0.00002073192,0.0001183172,0.9947764,0.0004525808,0.0001840243,0.002506751],"study_design_scores_gemma":[0.00002943291,0.0000552976,0.03775931,0.00000564962,0.00001349359,0.0001711238,0.00008812111,0.003488607,0.9526638,0.0005500346,0.005165174,0.000009981216],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9721681,0.001394759,0.01883652,0.0002735999,0.0000841115,0.00001614496,0.0005087761,0.0006701002,0.006047925],"genre_scores_gemma":[0.9876293,0.0002443331,0.003903176,0.0001071636,0.00001566416,0.000009701624,0.001104566,0.0001593639,0.006826841],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003014988,"threshold_uncertainty_score":0.01008612,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00853818470029873,"score_gpt":0.2509937709002616,"score_spread":0.2424555861999629,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}