{"id":"W2116958649","doi":"10.1016/j.yfrne.2012.06.002","title":"Neurodevelopmental effects of insulin-like growth factor signaling","year":2012,"lang":"en","type":"review","venue":"Frontiers in Neuroendocrinology","topic":"Growth Hormone and Insulin-like Growth Factors","field":"Medicine","cited_by":211,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of British Columbia","funders":"National Institute of Neurological Disorders and Stroke; Multiple Sclerosis Society","keywords":"Synaptogenesis; Insulin-like growth factor; Biology; Growth factor; Neuroscience; Axon guidance; Neural development; Signal transduction; Central nervous system; Axon; Cell biology; Receptor; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00005952989,0.001097624,0.00468329,0.001920328,0.0000687806,0.00001418853,0.0006078315,0.0004956921,0.00003622625],"category_scores_gemma":[0.0003564265,0.00097415,0.0008345941,0.001038509,0.0003267314,0.0001892131,0.0003560208,0.00190341,0.0000618956],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003086396,"about_ca_system_score_gemma":0.000464838,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000261733,"about_ca_topic_score_gemma":7.179004e-7,"domain_scores_codex":[0.994662,0.0005506718,0.001828307,0.001029906,0.0004727823,0.001456318],"domain_scores_gemma":[0.9975919,0.0004074833,0.0007706117,0.0007306158,0.0001108856,0.0003884833],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001689857,0.0007860613,0.02943445,0.05239009,0.0007429186,0.002406792,0.0002407861,1.353607e-7,0.00006732274,0.00008273643,0.003752075,0.9099277],"study_design_scores_gemma":[0.002588989,0.0008910687,0.01215156,0.004559772,0.002099585,0.001348271,0.00003104391,0.000002812491,0.0004102315,0.00004294932,0.9748837,0.0009900334],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.005158664,0.9840671,0.0001114593,0.00003276547,0.008156788,0.001980067,0.00004284588,0.0001335545,0.0003167564],"genre_scores_gemma":[0.006530148,0.9905019,0.001680697,0.0002928479,0.0002741561,0.0001715426,0.0001449961,0.0002254222,0.0001782995],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9711316,"threshold_uncertainty_score":0.9992709,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02992070886658129,"score_gpt":0.2758735317162332,"score_spread":0.2459528228496519,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}