{"id":"W2116967011","doi":"10.1097/01.moh.0000160737.52349.aa","title":"Hox regulation of normal and leukemic hematopoietic stem cells","year":2005,"lang":"en","type":"review","venue":"Current Opinion in Hematology","topic":"Developmental Biology and Gene Regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":162,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia; Genome Canada; Terry Fox Research Institute; BC Cancer Agency; Terry Fox Foundation","funders":"","keywords":"Hox gene; Biology; Haematopoiesis; Leukemia; Stem cell; Homeobox; Progenitor cell; Transplantation; Cancer research; Cell biology; Genetics; Gene; Transcription factor; Medicine; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001980967,0.0005358145,0.0006432885,0.0004802986,0.0001324681,0.0007172604,0.0003658463,0.0003988658,0.002349329],"category_scores_gemma":[0.0001978253,0.0001299933,0.000166581,0.0006005928,0.0003953032,0.0004786236,0.0005170858,0.0006084629,0.001536637],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004280419,"about_ca_system_score_gemma":0.0004223833,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003629655,"about_ca_topic_score_gemma":0.00033999,"domain_scores_codex":[0.9998865,0.00001286467,0.00001218616,0.00003902172,0.0000343219,0.00001509502],"domain_scores_gemma":[0.9999211,0.00001656625,0.00002141698,0.000004356471,0.00002086805,0.00001562781],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0003887879,0.00003792959,0.000712434,0.01859779,0.0001009331,0.0006898601,0.0001537151,0.0009057841,0.1068324,0.01248875,0.03369677,0.8253948],"study_design_scores_gemma":[0.00001386392,0.00008560488,0.003836493,0.0006940105,0.00007879471,0.001185138,0.00007093165,0.0001268465,0.01661833,0.001246896,0.9760278,0.00001516558],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.002010169,0.9933808,0.0007668879,0.0003638818,0.0007216461,0.00001063048,0.0001710729,0.00003511729,0.002539846],"genre_scores_gemma":[0.01211212,0.9824669,0.0004794407,0.0003615908,0.0007188027,0.0000168594,0.0003381416,0.00001591743,0.003490255],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002349329,"threshold_uncertainty_score":0.00785923,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04546028020521622,"score_gpt":0.3390306774841594,"score_spread":0.2935703972789432,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}