{"id":"W2116983037","doi":"10.1002/bdrb.20327","title":"Licorice extract increases cyclophosphamide teratogenicity by upregulating the expression of cytochrome P‐450 2B mRNA","year":2011,"lang":"en","type":"article","venue":"Birth Defects Research Part B Developmental and Reproductive Toxicology","topic":"Chemotherapy-induced organ toxicity mitigation","field":"Medicine","cited_by":13,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia Hospital","funders":"","keywords":"Cyclophosphamide; Fetus; Medicine; Gestation; Teratology; Internal medicine; Endocrinology; Pregnancy; Andrology; Chemotherapy; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006392392,0.0003819568,0.0003064367,0.0004469725,0.0001330256,0.0002001113,0.000129802,0.0002784499,0.001412155],"category_scores_gemma":[0.0001378058,0.0001341594,0.0001721901,0.000162709,0.0001959654,0.0001460772,0.0001214694,0.0004424363,0.000164858],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002197503,"about_ca_system_score_gemma":0.0001887649,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008143857,"about_ca_topic_score_gemma":0.001228613,"domain_scores_codex":[0.9999365,0.00001008448,0.000006627589,0.00001277623,0.0000160951,0.00001790125],"domain_scores_gemma":[0.9998802,0.000014227,0.00005744785,0.000009049713,0.00001239914,0.00002664789],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0007108166,0.0002724878,0.0007239451,0.00009510681,0.00001979814,0.00007626189,0.00001704867,0.00003654831,0.9943592,0.00002566411,0.00005344821,0.003609706],"study_design_scores_gemma":[0.000157618,0.004977014,0.02178551,0.00002411047,0.0001215105,0.0003780089,0.00004406727,0.0004473889,0.9697413,0.00002716648,0.002286699,0.000009596117],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9970229,0.001623905,0.000407584,0.00004337514,0.00001576286,0.00001876698,0.0001423866,0.00008741961,0.0006378742],"genre_scores_gemma":[0.9949664,0.001621816,0.0009291421,0.00005597112,0.00002468284,0.00003597781,0.0003423148,0.00001285596,0.002010739],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001412155,"threshold_uncertainty_score":0.004724145,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07084955513603647,"score_gpt":0.3194916578033493,"score_spread":0.2486421026673128,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}