{"id":"W2116983037","doi":"10.1002/bdrb.20327","title":"Licorice extract increases cyclophosphamide teratogenicity by upregulating the expression of cytochrome P‐450 2B mRNA","year":2011,"lang":"en","type":"article","venue":"Birth Defects Research Part B Developmental and Reproductive Toxicology","topic":"Chemotherapy-induced organ toxicity mitigation","field":"Medicine","cited_by":13,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia Hospital","funders":"","keywords":"Cyclophosphamide; Fetus; Medicine; Gestation; Teratology; Internal medicine; Endocrinology; Pregnancy; Andrology; Chemotherapy; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001605449,0.0002655986,0.0004534537,0.0001987494,0.0004779393,0.00002103123,0.0002068782,0.0002063305,0.0004193402],"category_scores_gemma":[0.001351176,0.0001845217,0.00007842492,0.0006463968,0.0008983582,0.0001924032,0.0003331109,0.0005924117,0.00002404544],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002279191,"about_ca_system_score_gemma":0.0003566525,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001858897,"about_ca_topic_score_gemma":0.00002764541,"domain_scores_codex":[0.9968548,0.0005495499,0.000503454,0.0008854272,0.000604434,0.0006023138],"domain_scores_gemma":[0.9983097,0.0004327889,0.0002078461,0.000465177,0.0003426654,0.0002417912],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006470225,0.0006181484,0.05467765,0.000122644,0.00009134859,0.00002947945,0.002346848,2.529131e-7,0.9356958,0.00004012372,0.001790239,0.003940408],"study_design_scores_gemma":[0.0007499561,0.0004950179,0.256679,0.0001189886,0.0000144944,0.0002714143,0.0007084868,0.000002774604,0.7392296,0.0002618473,0.001320018,0.0001484254],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9950762,0.001230263,0.00002157715,0.0004151007,0.00007867496,0.001323435,0.00001830619,0.00006035829,0.001776042],"genre_scores_gemma":[0.9962255,0.0003906948,0.00186859,0.000184221,0.0001939148,0.0001336632,0.00002450579,0.00004167002,0.0009372666],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2020014,"threshold_uncertainty_score":0.7524577,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07084955513603647,"score_gpt":0.3194916578033493,"score_spread":0.2486421026673128,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}