{"id":"W2117024122","doi":"10.1002/bit.25678","title":"A mathematical model and computational framework for three‐dimensional chondrocyte cell growth in a porous tissue scaffold placed inside a bi‐directional flow perfusion bioreactor","year":2015,"lang":"en","type":"article","venue":"Biotechnology and Bioengineering","topic":"Lattice Boltzmann Simulation Studies","field":"Engineering","cited_by":23,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Saskatchewan","funders":"Natural Sciences and Engineering Research Council of Canada; Saskatchewan Health Research Foundation","keywords":"Scaffold; Bioreactor; Biomedical engineering; Lattice Boltzmann methods; Porous medium; Biological system; Process (computing); Materials science; Mechanics; Fluid dynamics; Computer science; Chemistry; Porosity; Engineering; Biology; Physics; Composite material","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001285662,0.0002206727,0.0002702159,0.0003062861,0.00006545981,0.0000209773,0.00006283395,0.0004060304,0.00000261729],"category_scores_gemma":[0.00008811572,0.0002110138,0.00002329993,0.0002096206,0.00008729586,0.000105316,0.00008711926,0.000227149,0.000004438328],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007061349,"about_ca_system_score_gemma":0.00002288327,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000004286062,"about_ca_topic_score_gemma":0.00001153759,"domain_scores_codex":[0.999096,0.000005252572,0.0002495593,0.0002592459,0.0001350305,0.0002548915],"domain_scores_gemma":[0.9995561,0.0001862367,0.00002853574,0.00008908795,0.00005519572,0.00008490687],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"simulation_or_modeling","study_design_gemma":"simulation_or_modeling","study_design_scores_codex":[0.00007311954,0.00006150621,0.0004994185,0.0002149496,0.00005283435,0.00001050908,0.0003326777,0.9705637,0.01574412,0.01060031,0.0001164219,0.001730407],"study_design_scores_gemma":[0.0008302784,0.00006099426,0.000578222,0.00007262503,0.00001911532,0.00004575474,0.00003633207,0.9781124,0.005760245,0.01417566,0.00006714153,0.0002412428],"study_design_candidate":"simulation_or_modeling","study_design_consensus":"simulation_or_modeling","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.6772073,0.0009960957,0.320615,0.000362691,0.000101113,0.0002764391,0.00002601732,0.0003870334,0.00002827511],"genre_scores_gemma":[0.8278266,0.00002461436,0.1720035,0.00002013094,0.00003717709,0.00003918484,0.00001191551,0.00002820186,0.000008674339],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1506193,"threshold_uncertainty_score":0.8604894,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01926346830298684,"score_gpt":0.2358782040470368,"score_spread":0.21661473574405,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}