{"id":"W2117024122","doi":"10.1002/bit.25678","title":"A mathematical model and computational framework for three‐dimensional chondrocyte cell growth in a porous tissue scaffold placed inside a bi‐directional flow perfusion bioreactor","year":2015,"lang":"en","type":"article","venue":"Biotechnology and Bioengineering","topic":"Lattice Boltzmann Simulation Studies","field":"Engineering","cited_by":23,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Saskatchewan","funders":"Natural Sciences and Engineering Research Council of Canada; Saskatchewan Health Research Foundation","keywords":"Scaffold; Bioreactor; Biomedical engineering; Lattice Boltzmann methods; Porous medium; Biological system; Process (computing); Materials science; Mechanics; Fluid dynamics; Computer science; Chemistry; Porosity; Engineering; Biology; Physics; Composite material","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004246048,0.0008714562,0.0009744239,0.0007104879,0.0008755483,0.00136518,0.001965466,0.00205167,0.001559595],"category_scores_gemma":[0.0006424558,0.0006197979,0.001336471,0.0006718935,0.001012738,0.0007752185,0.001055841,0.001025994,0.0004353319],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00147611,"about_ca_system_score_gemma":0.002946552,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.02021836,"about_ca_topic_score_gemma":0.006824359,"domain_scores_codex":[0.9997398,0.0000580235,0.00001597929,0.00004353853,0.0001044454,0.00003822409],"domain_scores_gemma":[0.9997771,0.00008920689,0.00003547389,0.00001317529,0.00006089122,0.0000241155],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"simulation_or_modeling","study_design_gemma":"simulation_or_modeling","study_design_scores_codex":[0.00001189809,0.00002781843,0.0001974159,0.00004888242,0.000009749853,0.00007657213,0.00002948073,0.9814904,0.004217036,0.0124191,0.0001482923,0.001323322],"study_design_scores_gemma":[0.00000673863,0.000008726318,0.00004468,0.000004342352,0.000003599723,0.00001340704,0.000005666671,0.9983011,0.0003001721,0.0008241098,0.0004817573,0.000005829213],"study_design_candidate":"simulation_or_modeling","study_design_consensus":"simulation_or_modeling","genre_codex":"methods","genre_gemma":"empirical","genre_scores_codex":[0.0420604,0.001138168,0.939016,0.0007242346,0.0001513717,0.0001595079,0.0004127072,0.0003029475,0.01603473],"genre_scores_gemma":[0.689046,0.002998253,0.2860853,0.000384456,0.0001336389,0.001850517,0.0008077083,0.0002714537,0.01842271],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.02021836,"threshold_uncertainty_score":0.04020137,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01926346830298684,"score_gpt":0.2358782040470368,"score_spread":0.21661473574405,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}