{"id":"W2117049743","doi":"10.1148/radiol.13131041","title":"Mapping the Effect of the Apolipoprotein E Genotype on 4-Year Atrophy Rates in an Alzheimer Disease–related Brain Network","year":2014,"lang":"en","type":"article","venue":"Radiology","topic":"Dementia and Cognitive Impairment Research","field":"Medicine","cited_by":32,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Canadian Institutes of Health Research; National Institute on Aging; Amorfix Life Sciences; Eli Lilly and Company; National Institutes of Health; National Institute of Biomedical Imaging and Bioengineering; Alzheimer's Drug Discovery Foundation; Alzheimer's Association","keywords":"Atrophy; Apolipoprotein E; Alzheimer's Disease Neuroimaging Initiative; Medicine; Bonferroni correction; Neuroimaging; Magnetic resonance imaging; Alzheimer's disease; Internal medicine; Pathology; Neuroscience; Disease; Psychiatry; Psychology; Radiology","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001750418,0.0003447255,0.0002747922,0.0007820417,0.0002052927,0.0003696872,0.0003044298,0.0003526443,0.000785609],"category_scores_gemma":[0.004629951,0.0001678679,0.0004035206,0.0003233536,0.0002814055,0.0003490447,0.0002603678,0.000236346,0.000116265],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003075597,"about_ca_system_score_gemma":0.0002372925,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003814077,"about_ca_topic_score_gemma":0.005547802,"domain_scores_codex":[0.9994235,0.0002847918,0.00002974707,0.0001700667,0.0000527889,0.00003910917],"domain_scores_gemma":[0.9972766,0.001488917,0.0006859173,0.0002649056,0.0001347323,0.0001488931],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.004322463,0.0002399236,0.9557675,0.00004440773,0.0005245648,0.0001970688,0.0002182713,0.001205932,0.02358641,0.00005264283,0.000115671,0.0137252],"study_design_scores_gemma":[0.00002197527,0.0003646117,0.9963102,0.000003591102,0.00008657329,0.0001311356,0.00004410705,0.00169481,0.001215322,0.00005930782,0.00006361866,0.000004731082],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9994144,0.00006510293,0.0003772899,0.000009984535,0.00000101385,0.000005567043,0.00005662621,0.000004663063,0.00006523799],"genre_scores_gemma":[0.9988128,0.00003210229,0.0009396005,0.000006738253,0.000002026599,0.00001101213,0.0001118568,0.00000417543,0.00007965461],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003814077,"threshold_uncertainty_score":0.009257257,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01398465273839518,"score_gpt":0.2890392148901896,"score_spread":0.2750545621517944,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}