{"id":"W2117057469","doi":"10.1056/nejmoa1108524","title":"Antiretroviral Prophylaxis for HIV Prevention in Heterosexual Men and Women","year":2012,"lang":"en","type":"article","venue":"New England Journal of Medicine","topic":"HIV/AIDS Research and Interventions","field":"Medicine","cited_by":3309,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba","funders":"National Institute of Mental Health; Centers for Disease Control and Prevention; Gilead Sciences; Bill and Melinda Gates Foundation","keywords":"Medicine; Emtricitabine; Pre-exposure prophylaxis; Serodiscordant; Incidence (geometry); Interquartile range; Placebo; Confidence interval; Internal medicine; Randomized controlled trial; Men who have sex with men; Human immunodeficiency virus (HIV); Viral load; Antiretroviral therapy; Immunology; Syphilis","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001958238,0.0002450345,0.0005393028,0.0002420975,0.0003330456,0.0003469201,0.0002492428,0.0005575803,0.00473025],"category_scores_gemma":[0.002659,0.0001247227,0.0002803096,0.0002906501,0.0002377849,0.0002040268,0.0003564542,0.0006835193,0.0003016614],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002096271,"about_ca_system_score_gemma":0.0008698774,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004995101,"about_ca_topic_score_gemma":0.0008481519,"domain_scores_codex":[0.9991587,0.0005588842,0.00006090894,0.00003793854,0.0001186046,0.00006498815],"domain_scores_gemma":[0.9992679,0.0002635001,0.0002091999,0.00002455607,0.00003286138,0.0002019791],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.03225648,0.004559364,0.1973733,0.00474232,0.001099488,0.0005083455,0.0005276242,0.0002573645,0.001659396,0.001611735,0.01369041,0.7417142],"study_design_scores_gemma":[0.0984525,0.09509642,0.6010622,0.01176075,0.003226951,0.004993534,0.000811752,0.001433007,0.002590294,0.003240064,0.1772758,0.00005668226],"study_design_candidate":"randomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.7133453,0.2531945,0.00102596,0.01012789,0.001686072,0.002139062,0.0007946963,0.0000639464,0.01762265],"genre_scores_gemma":[0.9337574,0.05422711,0.00166743,0.004683641,0.001602633,0.001610959,0.0002829899,0.000004884002,0.002162776],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00473025,"threshold_uncertainty_score":0.01582426,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02949993270649761,"score_gpt":0.3453671009859945,"score_spread":0.3158671682794969,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}