{"id":"W2117084146","doi":"10.1016/j.jmb.2008.03.048","title":"Phage Display and Crystallographic Analysis Reveals Potential Substrate/Binding Site Interactions in the Protein Secretion Chaperone CsaA from Agrobacterium tumefaciens","year":2008,"lang":"en","type":"article","venue":"Journal of Molecular Biology","topic":"Bacterial Genetics and Biotechnology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":false,"ca_institutions":"Canada's Michael Smith Genome Sciences Centre; University of British Columbia; Simon Fraser University","funders":"National Institute of Allergy and Infectious Diseases","keywords":"Chaperone (clinical); Agrobacterium tumefaciens; Peptide; Binding site; Chemistry; Protein structure; Alanine; Phage display; Stereochemistry; Biophysics; Biochemistry; Biology; Amino acid; Transgene; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001185802,0.000209375,0.0002567892,0.0001858013,0.0003398554,0.0004322043,0.0003204941,0.0002688171,0.0008213374],"category_scores_gemma":[0.0001766041,0.0001633588,0.0002670529,0.0002766607,0.000199426,0.0001579342,0.0001487481,0.0007423282,0.0003265385],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005960538,"about_ca_system_score_gemma":0.0002801412,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002677902,"about_ca_topic_score_gemma":0.004242775,"domain_scores_codex":[0.9999284,0.0000101734,0.000004407646,0.00001265264,0.00003091211,0.00001355304],"domain_scores_gemma":[0.9998934,0.00003143802,0.00001769136,0.000008697514,0.00001506851,0.000033818],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003305856,0.00006969621,0.001714824,0.00003641459,0.00001416352,0.0002682628,0.0000708474,0.0007369901,0.9942923,0.0004582687,0.0002094422,0.001798357],"study_design_scores_gemma":[0.00004827631,0.0001040215,0.01457687,0.000007905159,0.00003913488,0.0007219687,0.0001216291,0.01175051,0.9694537,0.0001663046,0.002990721,0.00001892851],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9982121,0.0002037354,0.0009129161,0.0001215804,0.000009730052,0.000002906482,0.0001764174,0.00002765368,0.0003329538],"genre_scores_gemma":[0.9967291,0.0001684044,0.00143626,0.00003808213,0.000006135754,0.000005187446,0.0007045561,0.00002140423,0.0008908338],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002677902,"threshold_uncertainty_score":0.005324662,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008159731329014645,"score_gpt":0.2385738630609219,"score_spread":0.2304141317319073,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}