{"id":"W2117104552","doi":"10.3968/j.ans.1715787020120501.1065","title":"Endosymbiotic Actinidic Archaeal Synthesis of Neurotransmitters by Cholesterol Catabolism Regulates Brain Function","year":2012,"lang":"en","type":"article","venue":"Advances in natural science/Advances in natural sciences","topic":"Steroid Chemistry and Biochemistry","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Endomyocardial fibrosis; Mevalonate pathway; Cholesterol; Biology; Endocrinology; Catabolism; Internal medicine; Chemistry; Pharmacology; Biochemistry; Metabolism; Biosynthesis; Medicine; Enzyme","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.001097422,0.000372772,0.0003548224,0.0002042404,0.0002890143,0.00005517971,0.001279871,0.0001599731,0.000009860595],"category_scores_gemma":[0.0007187556,0.000298854,0.0001084571,0.001650472,0.002646707,0.0005935687,0.0002281904,0.0004307585,0.000001542543],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00008048984,"about_ca_system_score_gemma":0.0001312705,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003562159,"about_ca_topic_score_gemma":0.00008833357,"domain_scores_codex":[0.9965036,0.0000878163,0.0005588215,0.000952093,0.0007836638,0.001114014],"domain_scores_gemma":[0.9988502,0.0002197441,0.0003131941,0.0003618046,0.00007821439,0.0001768545],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001326413,0.00008459179,0.02461584,0.00007333295,0.000003810402,0.000001066148,0.00008049583,0.0001603711,0.9326268,0.00004062129,0.00004116007,0.0421393],"study_design_scores_gemma":[0.0004596268,0.0001188238,0.01506316,0.0001274652,0.000008072215,0.00003524687,0.0004224107,0.0000978071,0.9778391,0.0001855128,0.005228854,0.0004139951],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9254579,0.07184143,0.00001891113,0.0003030004,0.001422965,0.0002165681,0.00001896078,0.00001846489,0.0007017808],"genre_scores_gemma":[0.9953825,0.003453476,0.0004994336,0.0002715054,0.0002391162,0.00002999106,0.00002223552,0.00001220695,0.00008955306],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.06992456,"threshold_uncertainty_score":0.9999464,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004279396920753835,"score_gpt":0.2637253858174068,"score_spread":0.259445988896653,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}