{"id":"W2117113786","doi":"10.1158/0008-5472.can-08-1191","title":"<i>Helicobacter pylori</i> Cytotoxin-Associated Gene A Activates the Signal Transducer and Activator of Transcription 3 Pathway <i>In vitro</i> and <i>In vivo</i>","year":2009,"lang":"en","type":"article","venue":"Cancer Research","topic":"Helicobacter pylori-related gastroenterology studies","field":"Medicine","cited_by":156,"is_retracted":false,"has_abstract":true,"ca_institutions":"Queen's University; Hospital for Sick Children; University of Toronto","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Cancer Institute","keywords":"CagA; STAT3; Biology; STAT protein; Helicobacter pylori; Signal transduction; Transactivation; Carcinogenesis; Cancer research; Autocrine signalling; Molecular biology; Cell biology; Transcription factor; Receptor; Cancer; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001072575,0.0002509017,0.0005724019,0.0003271401,0.000123686,0.00002590181,0.0001445513,0.0002173824,0.00003874698],"category_scores_gemma":[0.00008773014,0.0001847226,0.00006858428,0.000746829,0.0004766877,0.0001873269,0.00003907919,0.001075148,0.00000120599],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002652118,"about_ca_system_score_gemma":0.0001669981,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003577785,"about_ca_topic_score_gemma":0.0003061889,"domain_scores_codex":[0.9973642,0.0004011812,0.0004538701,0.0005018354,0.0005079601,0.0007709322],"domain_scores_gemma":[0.9990422,0.000250102,0.00007645302,0.0002454875,0.0002246184,0.0001612051],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.003468886,0.0002832652,0.01977964,0.00005422054,0.000125671,0.00003734694,0.002196545,0.000002637149,0.9693131,0.000005783796,0.0001630082,0.004569896],"study_design_scores_gemma":[0.004302068,0.0006153331,0.1345975,0.0002502353,0.00003308523,0.0000193125,0.0003318395,0.00002530806,0.8587406,0.00006292521,0.0008959132,0.0001258976],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9851799,0.001591728,0.00000635321,0.01200796,0.00005427975,0.0008889883,0.00008992026,0.00002463307,0.0001562332],"genre_scores_gemma":[0.9965903,0.001978606,0.00002644409,0.001000205,0.00008867212,0.00016426,0.000008459983,0.00002909616,0.0001139573],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1148179,"threshold_uncertainty_score":0.7532767,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03591302373547205,"score_gpt":0.3136232499627349,"score_spread":0.2777102262272629,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}