{"id":"W2117139590","doi":"10.1007/s11538-008-9310-9","title":"A Geometric Comparison of Single Chain Multi-State Models of Ion Channel Gating","year":2008,"lang":"en","type":"article","venue":"Bulletin of Mathematical Biology","topic":"Ion channel regulation and function","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Guelph","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Gating; Chain (unit); Ion channel; Channel (broadcasting); Biological system; State (computer science); Computer science; Statistical physics; Mathematics; Topology (electrical circuits); Physics; Algorithm; Biophysics; Biology; Combinatorics; Telecommunications; Genetics; Quantum mechanics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001620973,0.0007369074,0.00138106,0.00111965,0.0009161286,0.001873695,0.002176824,0.001956394,0.007802647],"category_scores_gemma":[0.005067991,0.0005020698,0.001790114,0.0008004702,0.002042795,0.003773683,0.001429865,0.001441024,0.000490035],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002048691,"about_ca_system_score_gemma":0.001072338,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001514247,"about_ca_topic_score_gemma":0.001040986,"domain_scores_codex":[0.9994753,0.0002039645,0.00002552481,0.00008629796,0.0001213936,0.0000874976],"domain_scores_gemma":[0.9978122,0.001132613,0.0002503132,0.0002965461,0.0002591496,0.0002492089],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"theoretical_or_conceptual","study_design_gemma":"simulation_or_modeling","study_design_scores_codex":[0.00005636727,0.00003566143,0.0001889594,0.00003246068,0.00002227164,0.00005464564,0.00006813835,0.2534268,0.0008442613,0.74218,0.0008455505,0.002244934],"study_design_scores_gemma":[0.00001241704,0.00002887231,0.0001603237,0.000005568191,0.000007296647,0.00002698585,0.00001738147,0.776338,0.0001169114,0.2228812,0.0003877917,0.00001722281],"study_design_candidate":"simulation_or_modeling","study_design_consensus":null,"genre_codex":"methods","genre_gemma":"empirical","genre_scores_codex":[0.4085031,0.001548548,0.5275182,0.003552207,0.0004879505,0.000108583,0.0003688091,0.0003974439,0.05751519],"genre_scores_gemma":[0.9716761,0.0005949132,0.01887948,0.0003157382,0.0001500281,0.00009983527,0.0002106878,0.0001763543,0.007896879],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.007802647,"threshold_uncertainty_score":0.02610242,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06646534258168486,"score_gpt":0.2855985750924604,"score_spread":0.2191332325107755,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}