{"id":"W2117302579","doi":"10.1189/jlb.0506321","title":"CD4+ T cells stimulate memory CD8+ T cell expansion via acquired pMHC I complexes and costimulatory molecules, and IL-2 secretion","year":2006,"lang":"en","type":"article","venue":"Journal of Leukocyte Biology","topic":"T-cell and B-cell Immunology","field":"Immunology and Microbiology","cited_by":35,"is_retracted":false,"has_abstract":true,"ca_institutions":"Saskatchewan Cancer Agency; University of Saskatchewan","funders":"Canadian Institutes of Health Research; National Institutes of Health","keywords":"CD80; Cytotoxic T cell; Biology; Antigen-presenting cell; Cell biology; Interleukin 21; IL-2 receptor; Natural killer T cell; T cell; Streptamer; CD40; CD8; Secretion; Antigen; Immune system; In vitro; Immunology; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001152588,0.0005711017,0.0002088974,0.0002602693,0.0001091621,0.0003406891,0.0001530335,0.0003704553,0.004004119],"category_scores_gemma":[0.0001334652,0.0001413256,0.0002135969,0.0001360091,0.0001593844,0.0002239756,0.0003363249,0.0006007931,0.001284071],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001753746,"about_ca_system_score_gemma":0.0001337272,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001020018,"about_ca_topic_score_gemma":0.0001542208,"domain_scores_codex":[0.9998622,0.00003304668,0.000007443389,0.00001662532,0.00002161749,0.00005914192],"domain_scores_gemma":[0.9999192,0.00002150614,0.00001244643,0.00001019965,0.00000987246,0.00002685876],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000201499,0.0001293369,0.0006194023,0.0001536912,0.000009764762,0.0001515225,0.00002295699,0.000222617,0.9859805,0.0002842369,0.0005056986,0.01171878],"study_design_scores_gemma":[0.0003049093,0.002466652,0.008824273,0.00005241335,0.00004997188,0.001071251,0.000138804,0.002733353,0.9627485,0.001605337,0.01998966,0.00001479851],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9758348,0.00485133,0.005330984,0.000384808,0.0002053126,0.0001394973,0.0003734725,0.0002934446,0.01258645],"genre_scores_gemma":[0.9880896,0.001777621,0.003945609,0.0002234037,0.0001878803,0.00009521104,0.0003729907,0.00002532658,0.005282344],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004004119,"threshold_uncertainty_score":0.01339513,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009464441576049224,"score_gpt":0.2196986390661592,"score_spread":0.21023419749011,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}