{"id":"W2117312105","doi":"10.1093/molbev/msr005","title":"HIV-1 Modulates the tRNA Pool to Improve Translation Efficiency","year":2011,"lang":"en","type":"article","venue":"Molecular Biology and Evolution","topic":"RNA modifications and cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":130,"is_retracted":false,"has_abstract":true,"ca_institutions":"Jewish General Hospital; Ontario Genomics; University of Ottawa","funders":"Biotechnology and Biological Sciences Research Council","keywords":"Biology; Translation (biology); Transfer RNA; Human immunodeficiency virus (HIV); Computational biology; Evolutionary biology; Genetics; Virology; RNA; Gene; Messenger RNA","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001416538,0.00009964412,0.0000679915,0.00003369777,0.0001368721,0.00000758859,0.0001156515,0.0001322028,0.00001123509],"category_scores_gemma":[0.00002149003,0.00007366624,0.00004608514,0.00008369101,0.000101789,0.000003171029,0.00003276981,0.00005519884,0.00001499065],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000009569616,"about_ca_system_score_gemma":0.00002364276,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004670997,"about_ca_topic_score_gemma":0.00001001861,"domain_scores_codex":[0.9993269,0.00006471395,0.0001220945,0.0002808913,0.00003613282,0.0001692228],"domain_scores_gemma":[0.999621,0.000003732752,0.0000361334,0.0002479128,0.00004427907,0.0000469137],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005904125,0.00002789528,0.001761772,0.000002773677,0.00002114668,3.147002e-7,0.0001104857,0.00006221321,0.9866701,0.003932716,0.0001055635,0.007245959],"study_design_scores_gemma":[0.001162954,0.001293094,0.1121731,0.00001415456,0.0001031342,0.00003304029,0.0002428053,0.003049502,0.8571821,0.008486181,0.01562218,0.0006378285],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.7184992,0.001607853,0.2784672,0.0003490476,0.00009733281,0.0001991696,0.00001326489,0.000009857148,0.000756984],"genre_scores_gemma":[0.9985291,0.00005721519,0.000855457,0.0002567507,0.00005911253,0.00005671075,0.00004947489,0.000008719072,0.0001274202],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2800299,"threshold_uncertainty_score":0.3004022,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01020897866895293,"score_gpt":0.2442828558065152,"score_spread":0.2340738771375623,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}