{"id":"W2117319757","doi":"10.1016/j.metabol.2004.05.011","title":"Induction of the apolipoprotein AI promoter by Sp1 is repressed by saturated fatty acids","year":2004,"lang":"en","type":"article","venue":"Metabolism","topic":"Pancreatic function and diabetes","field":"Medicine","cited_by":24,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Calgary","funders":"","keywords":"Elaidic acid; Stearic acid; Oleic acid; Molecular biology; Fatty acid; Biochemistry; Chemistry; Reporter gene; Linoleic acid; Acetylation; Linolenic acid; Transfection; Biology; Gene expression; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004665473,0.0007666572,0.0005864674,0.001002974,0.0003951542,0.0009483764,0.0004536902,0.0003393495,0.002945504],"category_scores_gemma":[0.0004928837,0.0005707436,0.000738247,0.0003646062,0.0006512431,0.000386401,0.0007896048,0.001253197,0.001373533],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006506299,"about_ca_system_score_gemma":0.0003967117,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00114317,"about_ca_topic_score_gemma":0.00136094,"domain_scores_codex":[0.9995751,0.00008296153,0.00003309016,0.00008237096,0.00008063937,0.00014577],"domain_scores_gemma":[0.9991001,0.0002568049,0.0001393334,0.0001145751,0.0001216055,0.000267573],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004298197,0.00004185492,0.0004190163,0.00002140337,0.000006350067,0.00006238156,0.00003217893,0.00003486633,0.9975271,0.0002107212,0.00008317236,0.00113116],"study_design_scores_gemma":[0.00008058555,0.0003089852,0.01225605,0.0000245848,0.00002445315,0.0003866483,0.0002327967,0.001913439,0.9824725,0.0005266879,0.001756447,0.00001682152],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.989384,0.002150945,0.004530174,0.0004388083,0.0001404,0.00001782472,0.000616439,0.0002073878,0.002514135],"genre_scores_gemma":[0.9891652,0.0008085708,0.002773339,0.0001203382,0.000071762,0.00002843299,0.002073658,0.0001405262,0.004818149],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002945504,"threshold_uncertainty_score":0.009853721,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01088467569123652,"score_gpt":0.2431421767170459,"score_spread":0.2322575010258093,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}