{"id":"W2117380202","doi":"10.1016/j.healun.2011.02.008","title":"Pharmacokinetics in stable heart transplant recipients after conversion from twice-daily to once-daily tacrolimus formulations","year":2011,"lang":"en","type":"article","venue":"The Journal of Heart and Lung Transplantation","topic":"Transplantation: Methods and Outcomes","field":"Medicine","cited_by":28,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Alberta; University of Ottawa; Montreal Heart Institute","funders":"","keywords":"Tacrolimus; Pharmacokinetics; Medicine; Heart transplantation; Pharmacology; Internal medicine; Transplantation","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005582724,0.0002106662,0.000672077,0.0002023911,0.0002062037,0.0008233433,0.0001560197,0.0003779021,0.001326554],"category_scores_gemma":[0.001677115,0.0001621279,0.0004615482,0.0002075512,0.0003154044,0.0005469997,0.0001101883,0.0008614131,0.0003095599],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004970969,"about_ca_system_score_gemma":0.0003878987,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008255226,"about_ca_topic_score_gemma":0.0006975646,"domain_scores_codex":[0.9997333,0.00009577988,0.00001639263,0.00004040122,0.00005314234,0.00006091299],"domain_scores_gemma":[0.9995441,0.0001757258,0.0001064015,0.00003894758,0.0000369747,0.00009785232],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"observational","study_design_scores_codex":[0.3581329,0.007125837,0.1760023,0.0002572067,0.001249597,0.003362329,0.001266803,0.003859549,0.2911801,0.000658242,0.002063066,0.154842],"study_design_scores_gemma":[0.006553267,0.1396124,0.7560777,0.00004614503,0.00169402,0.003845749,0.0009667995,0.01171707,0.07497146,0.0006050351,0.003771539,0.0001387939],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9992406,0.0002841775,0.000091587,0.00002767058,0.00001256287,0.0000121389,0.0000487568,0.000007782482,0.0002748442],"genre_scores_gemma":[0.999438,0.000113176,0.00005730395,0.00004036199,0.00001287483,0.000007231981,0.00007688429,0.00000414191,0.0002501199],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001326554,"threshold_uncertainty_score":0.004437804,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03075991266385636,"score_gpt":0.3103926315991041,"score_spread":0.2796327189352477,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}