{"id":"W2117392589","doi":"10.1186/ar1433","title":"Long-term exposure of rheumatoid arthritis synovial fibroblasts to tumor necrosis factor alpha inhibits FasL-mediated apoptosis through activation of NF-κB and upregulation of the small ubiquitin-like modifier SUMO-1","year":2004,"lang":"en","type":"article","venue":"Arthritis Research","topic":"NF-κB Signaling Pathways","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Canadian Arthritis Network; School of Medicine, University of California, San Diego; Menzies Institute for Medical Research; National Cancer Institute; Arthritis Society; University of North Carolina at Chapel Hill; Genentech; National Institutes of Health; Biogen; Lupus Research Institute; Pfizer; Natural Sciences and Engineering Research Council of Canada; Dutch Arthritis Association; Oesterreichische Nationalbank; Deutsche Forschungsgemeinschaft; Nuffield Foundation; Physiotherapy Foundation of Canada; Canadian Institutes of Health Research; National Institute of Arthritis and Musculoskeletal and Skin Diseases; Lupus Research Alliance; Wellcome Trust; Newcastle University; National Institute of Allergy and Infectious Diseases; Howard Hughes Medical Institute; Austrian Science Fund; Arthritis Foundation","keywords":"Computer science","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004240218,0.0002149386,0.0003564488,0.0001407444,0.0001457484,0.00003454545,0.00030399,0.0002193099,0.00002835401],"category_scores_gemma":[0.0005512492,0.0002029114,0.0001253266,0.0004627671,0.0004200511,0.00002731586,0.0003766772,0.0002146363,0.000004002343],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004959869,"about_ca_system_score_gemma":0.0003281022,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004517256,"about_ca_topic_score_gemma":0.0005666135,"domain_scores_codex":[0.9975515,0.0002298381,0.0006156634,0.000495751,0.0006635041,0.0004437309],"domain_scores_gemma":[0.998311,0.0001115194,0.000237093,0.0005350593,0.0006860064,0.0001192751],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002221457,0.0001603126,0.007930222,0.0001067399,0.00004683095,0.000001268417,0.0008470127,0.0002335081,0.9806419,0.0001267019,0.00004052523,0.009642859],"study_design_scores_gemma":[0.001792194,0.0009029031,0.02090476,0.001076376,0.0000024878,0.00001177094,0.00008115231,0.00000928113,0.9747917,0.0001736856,0.00007618473,0.0001774734],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9975021,0.000599827,0.0005957596,0.0001688017,0.0000832146,0.0007709552,0.0002043742,0.00001197373,0.00006299774],"genre_scores_gemma":[0.9980364,0.001023825,0.0005727357,0.00004077152,0.00005144088,0.00006289822,0.0001262994,0.00004177626,0.00004385036],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01297453,"threshold_uncertainty_score":0.8274485,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03371674159085871,"score_gpt":0.2848339402799954,"score_spread":0.2511171986891367,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}