{"id":"W2117423509","doi":"10.1210/me.2005-0446","title":"Role and Regulation of Nodal/Activin Receptor-Like Kinase 7 Signaling Pathway in the Control of Ovarian Follicular Atresia","year":2006,"lang":"en","type":"article","venue":"Molecular Endocrinology","topic":"TGF-β signaling in diseases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":50,"is_retracted":false,"has_abstract":true,"ca_institutions":"York University; University of Ottawa","funders":"","keywords":"XIAP; Biology; Follicular atresia; Activin type 2 receptors; Activin receptor; ACVR2B; Protein kinase B; Cancer research; Endocrinology; Internal medicine; Cell biology; Signal transduction; Apoptosis; TGF beta signaling pathway; Ovarian follicle; Follicular phase; Transforming growth factor; Programmed cell death; Medicine; Caspase","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001140553,0.0002088208,0.0001616828,0.0001889612,0.0001399927,0.0003001911,0.0001350207,0.0002125835,0.0005706311],"category_scores_gemma":[0.00008624885,0.0000906816,0.0001603179,0.00007931219,0.0002445031,0.0002563425,0.0001888859,0.0003114806,0.0001392023],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002531069,"about_ca_system_score_gemma":0.0002340983,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002898446,"about_ca_topic_score_gemma":0.0003868371,"domain_scores_codex":[0.9999284,0.00002031931,0.000006307896,0.00001101192,0.00001169752,0.00002236196],"domain_scores_gemma":[0.9999448,0.000006854469,0.00001945048,0.000003308396,0.000007866892,0.00001769165],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005280809,0.00002542606,0.001416276,0.0001788013,0.00001496021,0.0007018756,0.00008842935,0.0002741793,0.9898426,0.001013419,0.0001007217,0.005815319],"study_design_scores_gemma":[0.0003103641,0.001133817,0.08401899,0.0001362131,0.0002135345,0.00315349,0.001190995,0.009435831,0.8749226,0.002765691,0.02267125,0.00004710122],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9661497,0.02736735,0.002631044,0.0003827857,0.00005751761,0.00003275574,0.0002078384,0.00006400345,0.003106965],"genre_scores_gemma":[0.990688,0.00678079,0.0009163295,0.00006571844,0.00002145381,0.00002212966,0.0001158585,0.000007301081,0.00138238],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0005706311,"threshold_uncertainty_score":0.001908958,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004001134491819153,"score_gpt":0.2045090406697988,"score_spread":0.2005079061779796,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}