{"id":"W2117426242","doi":"10.1186/1744-8069-7-59","title":"Cellular Prion Protein Protects from Inflammatory and Neuropathic Pain","year":2011,"lang":"en","type":"article","venue":"Molecular Pain","topic":"Prion Diseases and Protein Misfolding","field":"Biochemistry, Genetics and Molecular Biology","cited_by":27,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"Alberta Heritage Foundation for Medical Research; Canada Research Chairs; Fondation pour la Recherche Médicale; Hotchkiss Brain Institute, University of Calgary","keywords":"Nociception; Licking; NMDA receptor; Neuropathic pain; Spinal cord; Medicine; Glutamate receptor; Systemic administration; Biting; Pharmacology; Receptor; Internal medicine; Neuroscience; Endocrinology; Anesthesia; Biology; In vivo","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001592452,0.0004970144,0.0003893896,0.0004265094,0.0001254586,0.0002215264,0.0002482131,0.0004052468,0.0009183773],"category_scores_gemma":[0.0001708822,0.0001447403,0.0002370087,0.000163907,0.000276786,0.0001955794,0.0001666715,0.0006038017,0.00025089],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001032113,"about_ca_system_score_gemma":0.0001863563,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003329694,"about_ca_topic_score_gemma":0.0004041535,"domain_scores_codex":[0.999855,0.00002405414,0.00002037271,0.00002015901,0.00004522103,0.00003515965],"domain_scores_gemma":[0.9997657,0.0000220785,0.00007519333,0.00003496658,0.0000304899,0.0000716037],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004166374,0.0001018853,0.0001462073,0.00006799927,0.00001096662,0.00008522408,0.00001006507,0.00003219722,0.9975382,0.00005414853,0.00003317748,0.001503255],"study_design_scores_gemma":[0.0003197349,0.008013882,0.02983585,0.00006408599,0.0001317223,0.001753933,0.00007145655,0.001005076,0.954886,0.0002396378,0.003658382,0.00002037728],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9959664,0.002152052,0.00086729,0.00006580455,0.00003231314,0.00002413472,0.0002102822,0.00007646935,0.0006053098],"genre_scores_gemma":[0.9952623,0.001551085,0.0009054487,0.00005175227,0.00002373293,0.00003847762,0.0007088206,0.00001653867,0.001441846],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009183773,"threshold_uncertainty_score":0.003072321,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007904981890941583,"score_gpt":0.1832086410170202,"score_spread":0.1753036591260786,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}