{"id":"W2117427586","doi":"10.4049/jimmunol.1301722","title":"Identification of a Unique Hybrid Macrophage-Polarization State following Recovery from Lipopolysaccharide Tolerance","year":2013,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"IL-33, ST2, and ILC Pathways","field":"Immunology and Microbiology","cited_by":56,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Infection and Immunity","funders":"","keywords":"Proinflammatory cytokine; Lipopolysaccharide; Cell biology; Biology; Immune tolerance; Inflammation; Macrophage polarization; Transcription factor; Gene expression; Immunology; Gene; Phenotype; Immune system; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001500447,0.0001430591,0.0003369676,0.0002806462,0.000168622,0.0004141449,0.0001191336,0.0002299989,0.000677344],"category_scores_gemma":[0.0001924879,0.00009403617,0.0001960723,0.0001899062,0.0002431471,0.0001736587,0.0003377095,0.0005215351,0.0001962212],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001300773,"about_ca_system_score_gemma":0.0001113921,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001239531,"about_ca_topic_score_gemma":0.0001831714,"domain_scores_codex":[0.9998466,0.00001753367,0.00001096094,0.00003262767,0.00003493015,0.00005737518],"domain_scores_gemma":[0.9998295,0.00002069847,0.00005505934,0.00002041032,0.00003137578,0.00004297499],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002744849,0.00002561412,0.003456614,0.00001414565,0.000006855251,0.00007787478,0.00005059185,0.00002704467,0.9948139,0.00006032504,0.00001678153,0.001175695],"study_design_scores_gemma":[0.00003759401,0.001336433,0.3076054,0.00002824313,0.00006857824,0.001573595,0.001005062,0.001787959,0.6836897,0.00065927,0.00217493,0.00003322238],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9979841,0.0002325783,0.001288321,0.00003567833,0.000005893029,0.00001571092,0.0001764136,0.00002349973,0.0002378616],"genre_scores_gemma":[0.9985856,0.0001075172,0.0005423566,0.00005334272,0.000005955423,0.00003292624,0.0003269387,0.00000706498,0.0003383576],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.000677344,"threshold_uncertainty_score":0.00226593,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006455867938274267,"score_gpt":0.2061501670014845,"score_spread":0.1996942990632103,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}