{"id":"W2117442644","doi":"10.1093/glycob/cwq135","title":"Enzymatic synthesis and properties of glycoconjugates with legionaminic acid as a replacement for neuraminic acid","year":2010,"lang":"en","type":"article","venue":"Glycobiology","topic":"Glycosylation and Glycoproteins Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":36,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute for Biological Sciences","funders":"Simon Fraser University","keywords":"Glycoconjugate; Sialyltransferase; Biochemistry; Sialidase; Neuraminic acid; Sialic acid; Chemistry; Enzyme; Substrate (aquarium); Neuraminidase; Biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002498578,0.0004578821,0.0002608996,0.0001974543,0.0001118264,0.0003593663,0.0001823628,0.0002477107,0.0003039073],"category_scores_gemma":[0.0003378625,0.0001422611,0.0003038145,0.0003979025,0.0001654984,0.0001749125,0.0001982449,0.0002801549,0.0002889927],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003899743,"about_ca_system_score_gemma":0.0001828927,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00103027,"about_ca_topic_score_gemma":0.0009181678,"domain_scores_codex":[0.9997534,0.00005077512,0.00002884426,0.00003875062,0.0000822551,0.00004596162],"domain_scores_gemma":[0.9998106,0.00003040532,0.00003888303,0.00003186493,0.00004037373,0.00004790258],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003373042,0.000009469675,0.0001659961,0.00001414675,0.000003561363,0.00001814806,0.00000683144,0.00004598792,0.9990785,0.00001820213,0.000003499772,0.0006018925],"study_design_scores_gemma":[0.000003149687,0.00009833813,0.001236006,0.000001983717,0.000008254829,0.0000628547,0.000008891157,0.0001537188,0.9978772,0.000008653692,0.0005383818,0.000002623103],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9959652,0.0008186735,0.002102997,0.00002514414,0.00001111797,0.00002567124,0.0002974696,0.00002790073,0.0007257633],"genre_scores_gemma":[0.991058,0.0006714145,0.004974932,0.00002064946,0.00000603029,0.00002241809,0.001345566,0.00002830636,0.001872741],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00103027,"threshold_uncertainty_score":0.002829492,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01423979751901243,"score_gpt":0.2564165982331782,"score_spread":0.2421768007141658,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}