{"id":"W2117442644","doi":"10.1093/glycob/cwq135","title":"Enzymatic synthesis and properties of glycoconjugates with legionaminic acid as a replacement for neuraminic acid","year":2010,"lang":"en","type":"article","venue":"Glycobiology","topic":"Glycosylation and Glycoproteins Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":36,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute for Biological Sciences","funders":"Simon Fraser University","keywords":"Glycoconjugate; Sialyltransferase; Biochemistry; Sialidase; Neuraminic acid; Sialic acid; Chemistry; Enzyme; Substrate (aquarium); Neuraminidase; Biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002923934,0.0001842659,0.0002611376,0.00007805769,0.00009291987,0.00001787742,0.0001935115,0.0002152734,0.00005443399],"category_scores_gemma":[0.0006100414,0.0001331846,0.00006118944,0.0000694029,0.0004170248,0.000006387306,0.0001093547,0.0001298802,0.00001105342],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000005321883,"about_ca_system_score_gemma":0.0001360524,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002653315,"about_ca_topic_score_gemma":0.0001523009,"domain_scores_codex":[0.9988151,0.00007575689,0.0002789391,0.0004218909,0.00009869125,0.0003096734],"domain_scores_gemma":[0.9991381,0.00005079858,0.0001282999,0.0004183107,0.0001746609,0.00008983407],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001553232,0.00006565898,0.001789104,0.0001118668,0.00007954376,0.000001247876,0.00005174459,9.493181e-7,0.9933754,0.0004595991,0.0001619122,0.002349807],"study_design_scores_gemma":[0.0009802151,0.00209351,0.0006892801,0.00002690435,0.00002599278,0.0001246926,0.0001266884,0.00006152327,0.9805483,0.00009287058,0.01505042,0.0001796311],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.99755,0.0004742028,0.0001957217,0.000515183,0.000101809,0.000792438,0.00002468025,0.0000142086,0.0003318033],"genre_scores_gemma":[0.9973562,0.00008662523,0.001196778,0.0001615377,0.00008984047,0.000475419,0.0000455402,0.00002403462,0.0005639597],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01488851,"threshold_uncertainty_score":0.5431111,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01423979751901243,"score_gpt":0.2564165982331782,"score_spread":0.2421768007141658,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}