{"id":"W2117451443","doi":"10.1210/jcem.87.1.8164","title":"Orbital Fibroblast Heterogeneity May Determine the Clinical Presentation of Thyroid-Associated Ophthalmopathy","year":2002,"lang":"en","type":"article","venue":"The Journal of Clinical Endocrinology & Metabolism","topic":"Ophthalmology and Eye Disorders","field":"Medicine","cited_by":211,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Ottawa","funders":"National Institute of Dental and Craniofacial Research; National Eye Institute; Heart and Stroke Foundation of Canada; National Heart, Lung, and Blood Institute; National Institutes of Health; National Institute of Environmental Health Sciences; Canadian Institutes of Health Research; U.S. Department of Veterans Affairs","keywords":"Connective tissue; Adipogenesis; Adipose tissue; Fibroblast; Dermis; Biology; Extraocular muscles; Endocrinology; Population; Adipocyte; Internal medicine; Pathology; Cell biology; Cell culture; Anatomy; Medicine; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00365757,0.0002594151,0.001547919,0.0001161912,0.0001569875,0.000008813341,0.0006647361,0.0003536583,0.0004031007],"category_scores_gemma":[0.005755134,0.0001364298,0.001059778,0.0002597896,0.001596487,0.000143386,0.0001598611,0.001784295,0.00006187476],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001200047,"about_ca_system_score_gemma":0.0001083774,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002696942,"about_ca_topic_score_gemma":0.000007242623,"domain_scores_codex":[0.992805,0.002783824,0.003193525,0.0002455021,0.000470601,0.0005015522],"domain_scores_gemma":[0.992371,0.004191498,0.002134277,0.0006212278,0.0004749674,0.0002069958],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.009390481,0.007038941,0.9309943,0.00007584841,0.004657895,0.001972733,0.00108458,0.0001513053,0.002716566,0.0005525303,0.01207556,0.0292892],"study_design_scores_gemma":[0.008018585,0.003050882,0.9743447,0.00006685985,0.001557399,0.008318729,0.0003356761,0.0002424901,0.001266005,0.0007083864,0.001932415,0.0001579043],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9853525,0.004109454,0.00002450794,0.007598842,0.001421192,0.0003195667,0.000009806427,0.00001626402,0.001147842],"genre_scores_gemma":[0.9952308,0.002347762,0.000188928,0.0008328126,0.0009141454,0.000004006027,0.000003779829,0.00002673784,0.000451047],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.04335031,"threshold_uncertainty_score":0.7751974,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1175679905211693,"score_gpt":0.4187965565952192,"score_spread":0.3012285660740499,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}