{"id":"W2117507319","doi":"10.1083/jcb.201104121","title":"<i>Drosophila</i> ATM and ATR have distinct activities in the regulation of meiotic DNA damage and repair","year":2011,"lang":"en","type":"article","venue":"The Journal of Cell Biology","topic":"DNA Repair Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":136,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"","keywords":"Biology; DNA damage; DNA repair; Cell biology; G2-M DNA damage checkpoint; Ataxia-telangiectasia; Kinase; Meiosis; CHEK1; Homologous recombination; Phosphorylation; Checkpoint Kinase 2; DNA-PKcs; DNA; Genetics; Protein-Serine-Threonine Kinases; Cell cycle checkpoint; Protein kinase A; Cell cycle; Apoptosis; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007842145,0.00008498672,0.000148164,0.00003197739,0.00003541347,0.000003211141,0.0001479441,0.00009096661,0.000006471967],"category_scores_gemma":[0.00004881473,0.00004698032,0.00005025881,0.000029949,0.000226016,0.000005124847,0.00007375042,0.00009995377,1.794203e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000004543269,"about_ca_system_score_gemma":0.00002114045,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001735771,"about_ca_topic_score_gemma":0.00003661472,"domain_scores_codex":[0.9992163,0.0003108319,0.0002299333,0.00008644701,0.00005325833,0.0001032402],"domain_scores_gemma":[0.999427,0.00007356707,0.0002537402,0.0001875652,0.00003578586,0.00002234359],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002084965,0.00003286813,0.003086939,0.00001580155,0.00002173069,0.000001990264,0.0006128369,0.000001624189,0.9956071,0.0001647036,0.00004804562,0.0001978044],"study_design_scores_gemma":[0.0004800573,0.001009011,0.05124155,0.00001457005,0.00006399549,0.0001438793,0.0006663487,0.0000516844,0.9412724,0.004429694,0.0005452299,0.00008159137],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9979553,0.000778901,0.0000807719,0.00008922892,0.00005335315,0.00008077623,0.000003585011,0.000001882656,0.0009562487],"genre_scores_gemma":[0.9990851,0.0003300205,0.0003522469,0.00008895559,0.0000639933,8.30003e-7,0.00000269072,0.000006551695,0.00006956461],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.05433477,"threshold_uncertainty_score":0.1915802,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01321101188577814,"score_gpt":0.2217252317846764,"score_spread":0.2085142198988982,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}