{"id":"W2117532917","doi":"10.1111/j.1365-2958.2007.05678.x","title":"Growth phenotypes of <i>Pseudomonas aeruginosa lasR</i> mutants adapted to the airways of cystic fibrosis patients","year":2007,"lang":"en","type":"article","venue":"Molecular Microbiology","topic":"Bacterial biofilms and quorum sensing","field":"Biochemistry, Genetics and Molecular Biology","cited_by":350,"is_retracted":false,"has_abstract":true,"ca_institutions":"Armand Frappier Museum; Institut National de la Recherche Scientifique","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Institute of Allergy and Infectious Diseases","keywords":"Pseudomonas aeruginosa; Biology; Cystic fibrosis; Mutant; Microbiology; Phenotype; Chronic infection; Virulence; Biofilm; Multidrug tolerance; Mutation; Antibiotics; Gene; Bacteria; Immunology; Genetics; Immune system","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002576123,0.0002059977,0.0002880375,0.00006920275,0.00005488935,0.000006708904,0.0002828707,0.000230709,0.00001291545],"category_scores_gemma":[0.0001500803,0.0001610111,0.0001397046,0.0001906473,0.0001636947,0.000002341143,0.0002111744,0.00008152389,0.00001110479],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001105488,"about_ca_system_score_gemma":0.0000374428,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00007183669,"about_ca_topic_score_gemma":0.00004685618,"domain_scores_codex":[0.998679,0.000106319,0.0004206799,0.0003488278,0.0000673297,0.0003778352],"domain_scores_gemma":[0.9990462,0.00003243964,0.0001957258,0.0003984361,0.0002555856,0.00007162501],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003595791,0.00008406779,0.0009419735,0.00001961448,0.00006586057,0.000003270988,0.00005651202,0.00001319969,0.9965689,0.0001814862,0.0004602697,0.001245329],"study_design_scores_gemma":[0.0005191734,0.0006029693,0.002268035,0.0000227567,0.00003570564,0.00001459405,0.00002439573,8.961108e-7,0.9807352,0.000008451932,0.01559239,0.0001754277],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9964784,0.0003508924,0.001962719,0.0001146156,0.0002835282,0.0002790839,0.0001879129,0.000008126529,0.0003347324],"genre_scores_gemma":[0.9966998,0.00001397966,0.002355115,0.0005473836,0.0000629755,0.000002465577,0.0002680196,0.00002570743,0.00002457172],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01583363,"threshold_uncertainty_score":0.6565841,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.003973073930829736,"score_gpt":0.1972836437003057,"score_spread":0.1933105697694759,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}