{"id":"W2117556987","doi":"10.1093/emboj/cdf338","title":"Telencephalon‐specific Rb knockouts reveal enhanced neurogenesis, survival and abnormal cortical development","year":2002,"lang":"en","type":"article","venue":"The EMBO Journal","topic":"Cancer-related Molecular Pathways","field":"Medicine","cited_by":158,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Ottawa","funders":"Canadian Institutes of Health Research","keywords":"Biology; Neuroblast; Neurogenesis; Cell biology; Mitosis; Neural stem cell; Embryonic stem cell; Cell cycle; Retinoblastoma protein; Progenitor cell; Conditional gene knockout; Cerebrum; Cellular differentiation; Genetics; Stem cell; Neuroscience; Apoptosis; Central nervous system; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005248059,0.0002187604,0.0003186499,0.00009073481,0.0004325019,0.00006978988,0.0001764574,0.00008474842,0.0007699011],"category_scores_gemma":[0.00008596468,0.0001526451,0.0001013783,0.0001996135,0.0001569834,0.000076018,0.00007916515,0.0008381067,0.0001317048],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000127744,"about_ca_system_score_gemma":0.0001239224,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000002208149,"about_ca_topic_score_gemma":0.000003805398,"domain_scores_codex":[0.9980139,0.0001675864,0.0004866468,0.0002523607,0.0005984588,0.0004810481],"domain_scores_gemma":[0.9990023,0.00008714628,0.0001390687,0.000279261,0.0001266066,0.0003656154],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001317072,0.0008455737,0.00508719,0.000112525,0.000773456,0.003447404,0.007231806,0.0001193861,0.6940175,0.0005699396,0.02500482,0.2614733],"study_design_scores_gemma":[0.01563611,0.002050122,0.2793732,0.0009523781,0.0007846182,0.06227116,0.001496485,0.001018301,0.4574731,0.0002842334,0.1769608,0.001699541],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9873669,0.004703696,0.001476734,0.001162773,0.0007646635,0.0002366187,0.000002152221,0.00004674009,0.004239719],"genre_scores_gemma":[0.9955779,0.001713779,0.0009040086,0.0003218759,0.0005903066,0.000007757061,0.000001663058,0.00003904718,0.0008436167],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.274286,"threshold_uncertainty_score":0.8429877,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02773840623871006,"score_gpt":0.2419435818522705,"score_spread":0.2142051756135605,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}