{"id":"W2117575100","doi":"10.1210/en.2010-0605","title":"Activin A Regulates Porcine Follicle-Stimulating Hormone β-Subunit Transcription via Cooperative Actions of SMADs and FOXL2","year":2010,"lang":"en","type":"article","venue":"Endocrinology","topic":"TGF-β signaling in diseases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":46,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"Canadian Institutes of Health Research","keywords":"SMAD; Biology; Transcription factor; Activin type 2 receptors; Cell biology; Transcription (linguistics); Smad2 Protein; Gonadotropic cell; Protein subunit; ACVR2B; Molecular biology; Internal medicine; Endocrinology; Transforming growth factor; Gene; TGF beta signaling pathway; Genetics; Luteinizing hormone; Hormone","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0000494156,0.0001492549,0.0001828621,0.0000556857,0.0001108455,0.000009052151,0.0001054547,0.0001264613,0.00004166833],"category_scores_gemma":[0.0001187813,0.0001488272,0.00005467016,0.00007760362,0.0002144474,0.000008944445,0.00005776158,0.0001677046,0.00000301251],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000005671859,"about_ca_system_score_gemma":0.00004445647,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005211167,"about_ca_topic_score_gemma":0.0001305407,"domain_scores_codex":[0.9991303,0.00005827006,0.0002152374,0.0002888778,0.00006411431,0.0002432206],"domain_scores_gemma":[0.9994454,0.00004175763,0.00008945383,0.0002568974,0.00009784588,0.00006868311],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001390247,0.00009721044,0.002633691,0.00001043493,0.00007766302,0.000003375321,0.0001095896,0.0001157533,0.9914382,0.0002653376,0.00009809034,0.0050116],"study_design_scores_gemma":[0.0009448926,0.0005462651,0.02853115,0.000006212698,0.0000488072,0.00008125655,0.00008059658,0.0004117941,0.9659533,0.0001223482,0.003111392,0.0001620085],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9964857,0.0005793885,0.002184346,0.000173404,0.0001240098,0.0001544765,0.00002217233,0.00002749615,0.0002490782],"genre_scores_gemma":[0.9979518,0.0000317527,0.001431761,0.00004237969,0.0001279898,0.00002590528,0.00007752351,0.00002132254,0.0002895707],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02589745,"threshold_uncertainty_score":0.6068999,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01416263222377826,"score_gpt":0.2656567849556153,"score_spread":0.2514941527318371,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}