{"id":"W2117613982","doi":"10.1021/bi060354o","title":"RNA-Binding Affinities and Crystal Structure of Oligonucleotides Containing Five-Atom Amide-Based Backbone Structures<sup>,</sup>","year":2006,"lang":"en","type":"article","venue":"Biochemistry","topic":"DNA and Nucleic Acid Chemistry","field":"Biochemistry, Genetics and Molecular Biology","cited_by":37,"is_retracted":false,"has_abstract":true,"ca_institutions":"Concordia University","funders":"National Institute of General Medical Sciences","keywords":"Chemistry; Amide; DNA; Stereochemistry; Linker; Oligonucleotide; RNA; Nucleobase; Affinities; Nucleic acid; Crystallography; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00007938989,0.0003970013,0.0003581785,0.00004630684,0.000138601,0.00005897502,0.0002972077,0.0004500424,0.0001066031],"category_scores_gemma":[0.00007039568,0.0004052307,0.0001449055,0.0001016259,0.0004211798,0.000008995775,0.0001682877,0.0002011039,0.000001043792],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003088998,"about_ca_system_score_gemma":0.0001380113,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00006104245,"about_ca_topic_score_gemma":0.000005617871,"domain_scores_codex":[0.9982937,0.00002553015,0.0004321285,0.0005812132,0.0002445825,0.0004228722],"domain_scores_gemma":[0.9989794,0.00003534175,0.0002465171,0.0004839058,0.0001212843,0.0001335072],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001709676,0.00003399249,0.00504226,0.000252242,0.00006391171,0.000008717262,0.00003748714,0.0002634111,0.9926368,0.00006607614,0.001249592,0.0001745317],"study_design_scores_gemma":[0.001131649,0.00008966542,0.000880839,0.00007337138,0.0000494581,0.00004695943,0.000596497,0.0001707466,0.9951202,0.0001773499,0.001224854,0.000438369],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9961267,0.00105226,0.00008376414,0.00004236736,0.00004771052,0.0001049106,0.0003780773,0.00003836764,0.002125896],"genre_scores_gemma":[0.996274,0.00002699056,0.001782819,0.00008447648,0.0003921543,0.000004825155,0.0007495128,0.00005485723,0.0006303584],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004161421,"threshold_uncertainty_score":0.99984,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00480258236417948,"score_gpt":0.2030257681990678,"score_spread":0.1982231858348883,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}