{"id":"W2117637900","doi":"10.1128/jvi.01999-10","title":"Nuclear Envelope Disruption Involving Host Caspases Plays a Role in the Parvovirus Replication Cycle","year":2011,"lang":"en","type":"article","venue":"Journal of Virology","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":66,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; National Institutes of Health; Michael Smith Health Research BC","keywords":"Minute virus of mice; Biology; Parvovirus; Cell biology; Caspase; Viral replication; Parvoviridae; Nuclear lamina; Lamin; Virus; Cell nucleus; Viral envelope; Apoptosis; Molecular biology; Virology; Programmed cell death; Nuclear protein; Nucleus; Gene; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009640036,0.00009220483,0.0001345157,0.0000947019,0.00006537424,0.00001376797,0.0003766221,0.0001304323,0.00007209975],"category_scores_gemma":[0.0001656547,0.00006797026,0.00007360404,0.00009779728,0.00009306004,0.00001078487,0.00005899964,0.0002310002,0.00001983277],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000219883,"about_ca_system_score_gemma":0.00006499518,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004714424,"about_ca_topic_score_gemma":0.0002590854,"domain_scores_codex":[0.9988714,0.0003077602,0.0003030327,0.0001768878,0.0001354051,0.0002054905],"domain_scores_gemma":[0.9992526,0.00002821739,0.0002129107,0.0003806704,0.00007597989,0.00004966517],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002210299,0.0001542471,0.004817524,0.000003503428,0.00003302387,0.00003108778,0.0008816744,0.00004744772,0.9890996,0.0001015084,0.0002590968,0.002360951],"study_design_scores_gemma":[0.002915922,0.01568824,0.2033111,0.00003378919,0.00006125144,0.001243098,0.002140973,0.000540189,0.7578682,0.002241096,0.01352754,0.0004285128],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9979153,0.001048818,0.00005655597,0.0004083737,0.00004846278,0.0001021439,0.000002789043,0.000002601576,0.0004149492],"genre_scores_gemma":[0.9980412,0.0007926491,0.0001568251,0.0007815608,0.0001856566,0.000007068084,0.000005158074,0.00001614128,0.0000137729],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2312314,"threshold_uncertainty_score":0.2771747,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02965950723687957,"score_gpt":0.2963741879917311,"score_spread":0.2667146807548515,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}