{"id":"W2117637900","doi":"10.1128/jvi.01999-10","title":"Nuclear Envelope Disruption Involving Host Caspases Plays a Role in the Parvovirus Replication Cycle","year":2011,"lang":"en","type":"article","venue":"Journal of Virology","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":66,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; National Institutes of Health; Michael Smith Health Research BC","keywords":"Minute virus of mice; Biology; Parvovirus; Cell biology; Caspase; Viral replication; Parvoviridae; Nuclear lamina; Lamin; Virus; Cell nucleus; Viral envelope; Apoptosis; Molecular biology; Virology; Programmed cell death; Nuclear protein; Nucleus; Gene; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003083643,0.0003637012,0.0003650225,0.0002450132,0.0003705427,0.0007878657,0.000261514,0.000447153,0.001154216],"category_scores_gemma":[0.0003925697,0.0001456337,0.0002534046,0.0001212353,0.0004566403,0.0009274821,0.0003616013,0.0005674206,0.0004004154],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006934756,"about_ca_system_score_gemma":0.000359448,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002020038,"about_ca_topic_score_gemma":0.0001856163,"domain_scores_codex":[0.9998112,0.00004108988,0.00001657095,0.00004417677,0.00004535172,0.00004154713],"domain_scores_gemma":[0.9997513,0.00006053466,0.00005935719,0.00003459551,0.00004932673,0.00004484868],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000525952,0.00007825493,0.001018684,0.0001071414,0.0000084638,0.0002201373,0.00006690231,0.0002390072,0.9894937,0.001616696,0.0001157538,0.006509203],"study_design_scores_gemma":[0.000073646,0.000479159,0.008257515,0.00002326313,0.00001712993,0.001042045,0.0001106355,0.002111442,0.9784782,0.001314643,0.008076102,0.00001633683],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9639052,0.01815271,0.01302063,0.0003699564,0.00007748193,0.00006828328,0.0001936822,0.000273168,0.003938845],"genre_scores_gemma":[0.9942186,0.002016103,0.002528526,0.00002601816,0.00001511961,0.00002096414,0.00009148065,0.00001151785,0.001071706],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001154216,"threshold_uncertainty_score":0.005031526,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02965950723687957,"score_gpt":0.2963741879917311,"score_spread":0.2667146807548515,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}