{"id":"W2117719235","doi":"10.2967/jnumed.112.105908","title":"In Vivo Measurement of the Affinity and Density of Metabotropic Glutamate Receptor Subtype 1 in Rat Brain Using <sup>18</sup>F-FITM in Small-Animal PET","year":2012,"lang":"en","type":"article","venue":"Journal of Nuclear Medicine","topic":"Neuroscience and Neuropharmacology Research","field":"Neuroscience","cited_by":24,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Institute of Genetics; Ministry of Education, Culture, Sports, Science and Technology","keywords":"Radioligand; Ligand (biochemistry); In vivo; Metabotropic glutamate receptor; Dissociation constant; Chemistry; Metabotropic glutamate receptor 1; Receptor; Binding potential; Glutamate receptor; Radioligand Assay; Stereochemistry; Biochemistry; Biology","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002766415,0.0001239677,0.0004607162,0.0004008333,0.00005265227,0.000006541819,0.0003718285,0.00004205075,0.0001869538],"category_scores_gemma":[0.003219626,0.00008131912,0.00005229574,0.0007396512,0.0005097243,0.0002821864,0.0001668387,0.0006372995,0.000001572549],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00008746898,"about_ca_system_score_gemma":0.0001112023,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00006122645,"about_ca_topic_score_gemma":0.0000264762,"domain_scores_codex":[0.9971727,0.0009617244,0.0006479239,0.0001765055,0.000690353,0.0003508434],"domain_scores_gemma":[0.9988499,0.0003850509,0.000383589,0.0001512485,0.0001033052,0.0001269606],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005293871,0.0002377654,0.04854191,0.00004165664,0.00000259341,0.00009984519,0.0006460194,0.00004798221,0.9493995,0.00003508472,0.0003772936,0.00004101775],"study_design_scores_gemma":[0.003706197,0.001163191,0.1606023,0.0003844312,0.00003877994,0.0004465686,0.000414614,0.001330056,0.8304719,0.0000411967,0.00126873,0.0001320366],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9951615,0.0001280108,5.104114e-7,0.004067304,0.0004221491,0.0001891348,0.00000145952,0.000002018713,0.0000279559],"genre_scores_gemma":[0.9985675,0.0002004408,0.00003507451,0.001074106,0.00009751247,4.672401e-7,6.865746e-9,0.000012941,0.00001200295],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1189276,"threshold_uncertainty_score":0.3854425,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1279578116268212,"score_gpt":0.3431385337561257,"score_spread":0.2151807221293045,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}