{"id":"W2117786106","doi":"10.1093/emboj/cdf447","title":"Leishmania LPG3 encodes a GRP94 homolog required for phosphoglycan synthesis implicated in parasite virulence but not viability","year":2002,"lang":"en","type":"article","venue":"The EMBO Journal","topic":"Research on Leishmaniasis Studies","field":"Medicine","cited_by":83,"is_retracted":false,"has_abstract":false,"ca_institutions":"Institut National de la Recherche Scientifique","funders":"National Institute of Allergy and Infectious Diseases; Canadian Institutes of Health Research; National Institutes of Health; McMaster University","keywords":"Biology; Lipophosphoglycan; Mutant; Endoplasmic reticulum; Glycoconjugate; Cell biology; Virulence; Leishmania; Biochemistry; Leishmania donovani; Parasite hosting; Genetics; Gene; Leishmaniasis","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0000927654,0.0006453136,0.0003436538,0.0004473229,0.0002545068,0.0004605016,0.0005175817,0.000480474,0.002249614],"category_scores_gemma":[0.0002572481,0.0002199272,0.0004297024,0.0004756947,0.000422381,0.0002181605,0.0004124054,0.0008271147,0.002086851],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006129509,"about_ca_system_score_gemma":0.0002750477,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00102611,"about_ca_topic_score_gemma":0.0009407839,"domain_scores_codex":[0.999903,0.0000166657,0.000007961916,0.00002015713,0.00002872355,0.00002354808],"domain_scores_gemma":[0.9997539,0.00004983315,0.00006751718,0.00004085068,0.00002087804,0.00006697706],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001773511,0.00001190884,0.0001462844,0.00002327913,0.00000557027,0.00030398,0.000008283002,0.00004142647,0.9977542,0.0001001207,0.0001790268,0.0012486],"study_design_scores_gemma":[0.00006693477,0.0001318579,0.006802334,0.000009753465,0.00003855081,0.002563124,0.00007287019,0.001246032,0.9824759,0.0001768745,0.006399063,0.00001665949],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9793419,0.001025729,0.009041624,0.0005890843,0.0001224873,0.00007518433,0.006390397,0.001231618,0.002182018],"genre_scores_gemma":[0.9797569,0.0003531838,0.005447427,0.0001678546,0.00002335051,0.00004837042,0.01013188,0.0002714481,0.003799558],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002249614,"threshold_uncertainty_score":0.007525742,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06085686595147576,"score_gpt":0.3217835841890868,"score_spread":0.260926718237611,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}