{"id":"W2117841430","doi":"10.1101/gad.860301","title":"Nuclear translocation controlled by alternatively spliced isoforms inactivates the QUAKING apoptotic inducer","year":2001,"lang":"en","type":"article","venue":"Genes & Development","topic":"Cell death mechanisms and regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":102,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Jewish General Hospital","funders":"Canadian Institutes of Health Research; Multiple Sclerosis Society; Multiple Sclerosis Society of Canada","keywords":"Biology; Gene isoform; Caenorhabditis elegans; Cell biology; Chromosomal translocation; Apoptosis; Alternative splicing; Molecular biology; Gene; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002109713,0.0001522494,0.0001368287,0.00002899192,0.0002312615,0.00003853757,0.0001486552,0.00009730682,0.00003659185],"category_scores_gemma":[0.000007858021,0.0001003902,0.00005597136,0.00007437319,0.00002570687,0.000006391929,0.00003917703,0.00005311685,0.00001609293],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003623967,"about_ca_system_score_gemma":0.00005570837,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002084051,"about_ca_topic_score_gemma":0.00001962493,"domain_scores_codex":[0.9991143,0.00003497048,0.0002394883,0.0002460053,0.0001578252,0.0002073605],"domain_scores_gemma":[0.9996292,0.000008612654,0.0001073406,0.0001569048,0.00005530574,0.00004261833],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001546215,0.00004201993,0.0001159162,0.000004086967,0.00008759246,5.305218e-7,0.0004036427,0.00007938796,0.8742155,0.0001835077,0.0001219183,0.1245913],"study_design_scores_gemma":[0.002250975,0.00008725089,0.003448034,0.00001908743,0.00002139564,0.00001545243,0.0003977321,0.0004684206,0.8296973,0.0001166266,0.16319,0.0002877013],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9882095,0.001086222,0.009424236,0.0003266085,0.0001544738,0.000400265,0.000001073181,0.00001664735,0.0003809179],"genre_scores_gemma":[0.9966098,0.001090822,0.0009568636,0.0002735486,0.000106387,0.0000575302,0.00008696103,0.00002306627,0.0007950376],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1630681,"threshold_uncertainty_score":0.4093794,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008799658641032314,"score_gpt":0.2247078888085473,"score_spread":0.2159082301675149,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}