{"id":"W2117875949","doi":"10.1155/2010/985137","title":"Investigation of Genipin Cross-Linked Microcapsule for Oral Delivery of Live Bacterial Cells and Other Biotherapeutics: Preparation and In Vitro Analysis in Simulated Human Gastrointestinal Model","year":2010,"lang":"en","type":"article","venue":"International Journal of Polymer Science","topic":"Advanced Drug Delivery Systems","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":16,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; Fonds Québécois de la Recherche sur la Nature et les Technologies","keywords":"Genipin; Dextran; In vitro; Chitosan; Gastrointestinal tract; Materials science; In vivo; Chemistry; Chromatography; Biochemistry; Biotechnology; Biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002581592,0.00033903,0.0002439854,0.0001548903,0.0001158125,0.0001610865,0.0001154106,0.0003188027,0.0002127141],"category_scores_gemma":[0.0002263776,0.0001200307,0.0002134534,0.0001181247,0.0002076937,0.0002056067,0.0001071463,0.0002120559,0.00008625797],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002691952,"about_ca_system_score_gemma":0.0001949112,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009323455,"about_ca_topic_score_gemma":0.001116269,"domain_scores_codex":[0.9998984,0.00001951348,0.000007596888,0.00002870111,0.00002988687,0.00001580627],"domain_scores_gemma":[0.999878,0.0000435401,0.00003449424,0.000009185511,0.00002173305,0.00001311464],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003916124,0.00001147434,0.00008293654,0.00005064493,0.000003799993,0.00003354542,0.00001667279,0.0001442604,0.9985795,0.0000167893,0.000006030951,0.001015266],"study_design_scores_gemma":[0.000003374658,0.0004671581,0.001328934,0.000004228864,0.00001522035,0.00009390331,0.00001209432,0.000615951,0.9969016,0.000008382027,0.0005449163,0.000004241377],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.992018,0.003057885,0.004389605,0.00004653175,0.00001829251,0.00004621493,0.0000889675,0.00002383012,0.0003106962],"genre_scores_gemma":[0.9894505,0.002011535,0.007664599,0.00003351162,0.000007323336,0.0000534942,0.000114239,0.00001119391,0.0006536721],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009323455,"threshold_uncertainty_score":0.001953125,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07072209156207233,"score_gpt":0.4318874004204942,"score_spread":0.3611653088584219,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}