{"id":"W2117875949","doi":"10.1155/2010/985137","title":"Investigation of Genipin Cross-Linked Microcapsule for Oral Delivery of Live Bacterial Cells and Other Biotherapeutics: Preparation and In Vitro Analysis in Simulated Human Gastrointestinal Model","year":2010,"lang":"en","type":"article","venue":"International Journal of Polymer Science","topic":"Advanced Drug Delivery Systems","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":16,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; Fonds Québécois de la Recherche sur la Nature et les Technologies","keywords":"Genipin; Dextran; In vitro; Chitosan; Gastrointestinal tract; Materials science; In vivo; Chemistry; Chromatography; Biochemistry; Biotechnology; Biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009586058,0.00009809919,0.0002356423,0.0006565902,0.00003611477,0.00002763659,0.0002706719,0.00006931875,0.00001563902],"category_scores_gemma":[0.00005108689,0.00009467847,0.00005465169,0.0002657113,0.0006625532,0.0003882637,0.00004582255,0.0002198013,1.862561e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000048089,"about_ca_system_score_gemma":0.0001664426,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00009311343,"about_ca_topic_score_gemma":0.000143961,"domain_scores_codex":[0.9987296,0.00007892308,0.0006599645,0.0001710411,0.0002188481,0.0001416307],"domain_scores_gemma":[0.9985747,0.0001655732,0.0006255228,0.00006355523,0.000494869,0.00007577468],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001082547,0.00005688529,0.05498367,0.000008416586,0.00006746974,0.000002270704,0.001121975,0.01388723,0.9282727,0.00003710347,9.401994e-7,0.0004788168],"study_design_scores_gemma":[0.001314246,0.0000908526,0.007078492,0.00002043087,0.00004640744,0.00002128421,0.00003979599,0.2590422,0.7321334,0.0001445726,0.000007761217,0.000060501],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9979484,0.0001187078,0.001382769,0.00004014411,0.000293324,0.0001383531,0.00007022487,0.000003272134,0.000004817432],"genre_scores_gemma":[0.9966355,0.000008658968,0.003186772,0.0000874286,0.00005643432,0.000001713118,0.000003378385,0.000007107476,0.00001300262],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.245155,"threshold_uncertainty_score":0.3860876,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07072209156207233,"score_gpt":0.4318874004204942,"score_spread":0.3611653088584219,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}