{"id":"W2117902695","doi":"10.1002/jgm.624","title":"Heterogeneity of the immune response to adenovirus‐mediated factor VIII gene therapy in different inbred hemophilic mouse strains","year":2004,"lang":"en","type":"article","venue":"The Journal of Gene Medicine","topic":"Hemophilia Treatment and Research","field":"Medicine","cited_by":30,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University; Queen's University","funders":"Canadian Blood Services; Canada Research Chairs; Heart and Stroke Foundation of Canada","keywords":"Immune system; Genetic enhancement; Biology; Factor IX; Gene; Inbred strain; Virology; Immunology; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001722003,0.0002900156,0.0008510834,0.0004254837,0.0001005142,0.000005574315,0.0005603538,0.0001170789,0.000122557],"category_scores_gemma":[0.0007177416,0.0001157417,0.0002235434,0.0006784052,0.000357881,0.00004568211,0.00008628017,0.0006181541,0.000007831221],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003642438,"about_ca_system_score_gemma":0.0003998282,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001122055,"about_ca_topic_score_gemma":0.00004205859,"domain_scores_codex":[0.99666,0.0005640438,0.00101152,0.0001644725,0.001188522,0.0004114669],"domain_scores_gemma":[0.998019,0.0003290666,0.0003734658,0.0006753187,0.0002843886,0.0003187859],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.008392799,0.0005881357,0.00650579,0.00002055848,0.0002653389,0.0001032899,0.003929257,0.00009448364,0.9784312,0.000001177816,0.00004986944,0.001618117],"study_design_scores_gemma":[0.009371967,0.003501352,0.3775551,0.0002307986,0.00006749604,0.0002438959,0.0003197219,0.000005610038,0.6085013,0.00002924506,0.00009893543,0.00007457612],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9587479,0.00340422,0.00003779839,0.03674042,0.0001957506,0.0008232584,0.00002200862,0.00000971282,0.00001896532],"genre_scores_gemma":[0.9969442,0.001721138,0.00006574971,0.0006212497,0.0003789699,0.00000608846,0.00000515181,0.00003583913,0.0002215844],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3710493,"threshold_uncertainty_score":0.471981,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05228400790326036,"score_gpt":0.3284386786168203,"score_spread":0.2761546707135599,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}