{"id":"W2117907239","doi":"10.1902/jop.2009.090251","title":"Grape Seed Extract Suppresses Lipopolysaccharide‐Induced Matrix Metalloproteinase (MMP) Secretion by Macrophages and Inhibits Human MMP‐1 and −9 Activities","year":2009,"lang":"en","type":"article","venue":"Journal of Periodontology","topic":"Oral microbiology and periodontitis research","field":"Dentistry","cited_by":46,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval","funders":"Canadian Institutes of Health Research","keywords":"Matrix metalloproteinase; Secretion; Lipopolysaccharide; Aggregatibacter actinomycetemcomitans; Grape seed extract; Periodontal pathogen; Recombinant DNA; Chemistry; Periodontitis; Microbiology; Molecular biology; Biology; Biochemistry; Porphyromonas gingivalis; Immunology; Medicine; Internal medicine; Pathology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001051016,0.0003379245,0.0003307415,0.0002097859,0.000112748,0.0001518644,0.0001162937,0.0001967339,0.0007490573],"category_scores_gemma":[0.0001378147,0.00009843487,0.0003504244,0.000117531,0.0001775617,0.000103014,0.0001184475,0.0003131193,0.0001522842],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001248369,"about_ca_system_score_gemma":0.0001458884,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006629713,"about_ca_topic_score_gemma":0.000754074,"domain_scores_codex":[0.9999436,0.00001503936,0.000006424204,0.00001005777,0.00001102533,0.00001389715],"domain_scores_gemma":[0.9999334,0.00001378572,0.00001498272,0.000006288467,0.00001029363,0.00002128495],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001144199,0.0003320812,0.0003508348,0.0001977978,0.00003719018,0.00008297487,0.00002802447,0.00005783516,0.9945503,0.00001776158,0.0001034863,0.003097516],"study_design_scores_gemma":[0.0004441755,0.01079315,0.03522265,0.00005343268,0.0001893188,0.0006872912,0.00009552404,0.001143752,0.9472611,0.00008803185,0.00400069,0.00002088913],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9969575,0.002103707,0.0002628264,0.00005893503,0.00003098744,0.00002236177,0.00009415743,0.00004640648,0.0004229529],"genre_scores_gemma":[0.9967829,0.001429684,0.0006069961,0.00008179286,0.00002439862,0.00001674178,0.0003026615,0.00000948133,0.0007453386],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007490573,"threshold_uncertainty_score":0.002505839,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01451758379874371,"score_gpt":0.3173355331799893,"score_spread":0.3028179493812456,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}