{"id":"W2117912433","doi":"10.3390/v3112146","title":"Activation of LTRs from Different Human Endogenous Retrovirus (HERV) Families by the HTLV-1 Tax Protein and T-Cell Activators","year":2011,"lang":"en","type":"article","venue":"Viruses","topic":"T-cell and Retrovirus Studies","field":"Immunology and Microbiology","cited_by":67,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université du Québec à Montréal","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Jurkat cells; Transactivation; Long terminal repeat; Tropical spastic paraparesis; Biology; Transfection; Provirus; Expression vector; CREB; Retrovirus; Gene expression; Virology; Molecular biology; Cell biology; Gene; Genetics; Transcription factor; T cell; Recombinant DNA; Genome; Immune system","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007317129,0.0002495289,0.0003373999,0.00006565042,0.0004121739,0.00001088709,0.000229022,0.0001976354,0.000274932],"category_scores_gemma":[0.00003344223,0.0001503441,0.00007303451,0.00007273228,0.0005489322,0.00009860338,0.0001508572,0.0002592605,0.00004418402],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002518428,"about_ca_system_score_gemma":0.00001587417,"about_ca_topic_candidate":true,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.009496421,"about_ca_topic_score_gemma":0.0001515408,"domain_scores_codex":[0.998905,0.0001805466,0.0002880174,0.0002943912,0.00005608498,0.0002759862],"domain_scores_gemma":[0.999271,0.0001346274,0.0002403025,0.0003008182,0.00003374583,0.00001946803],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001757964,0.0002525993,0.01140256,0.00002129768,0.0002192898,7.221321e-7,0.003071287,4.526297e-8,0.9814569,0.0001942186,0.001284731,0.001920527],"study_design_scores_gemma":[0.0007255282,0.0003260675,0.01085339,0.00002988781,0.00005698427,0.00000158727,0.001704172,6.547813e-8,0.9786562,0.0002546824,0.007214932,0.0001764871],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9927131,0.003721161,0.00001595126,0.0000237272,0.0001723358,0.0004004772,0.0001975607,0.00005587213,0.002699797],"genre_scores_gemma":[0.9984952,0.0003079757,0.00001563357,0.0001120153,0.00002832287,0.00005793735,0.00003059396,0.00002283013,0.000929456],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00934488,"threshold_uncertainty_score":0.9970994,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04013836545499838,"score_gpt":0.2178151995295524,"score_spread":0.177676834074554,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}