{"id":"W2117912433","doi":"10.3390/v3112146","title":"Activation of LTRs from Different Human Endogenous Retrovirus (HERV) Families by the HTLV-1 Tax Protein and T-Cell Activators","year":2011,"lang":"en","type":"article","venue":"Viruses","topic":"T-cell and Retrovirus Studies","field":"Immunology and Microbiology","cited_by":67,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université du Québec à Montréal","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Jurkat cells; Transactivation; Long terminal repeat; Tropical spastic paraparesis; Biology; Transfection; Provirus; Expression vector; CREB; Retrovirus; Gene expression; Virology; Molecular biology; Cell biology; Gene; Genetics; Transcription factor; T cell; Recombinant DNA; Genome; Immune system","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002389929,0.0003151288,0.0002624725,0.0002729009,0.0001729387,0.000459438,0.000245091,0.000298774,0.001374929],"category_scores_gemma":[0.0002036952,0.0001558851,0.0004455672,0.0002885195,0.0002494691,0.0003609938,0.0002275689,0.0006701579,0.0006456336],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005015621,"about_ca_system_score_gemma":0.0002034972,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004329954,"about_ca_topic_score_gemma":0.000685301,"domain_scores_codex":[0.9996706,0.00006768619,0.00003135994,0.00007106486,0.00008742027,0.00007180832],"domain_scores_gemma":[0.999891,0.00002796661,0.00003002921,0.00002148052,0.00001482394,0.00001469531],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001030085,0.0000311661,0.0003953598,0.00004736409,0.000006431709,0.00005108187,0.00003012428,0.0000789938,0.9972298,0.000278337,0.0000349929,0.001713488],"study_design_scores_gemma":[0.00001845614,0.0002377654,0.003084912,0.00001833779,0.00002264004,0.0004872143,0.00009454435,0.001100383,0.9908042,0.0001370681,0.00398582,0.000008666892],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9891295,0.002236617,0.006013418,0.00007962094,0.00003818055,0.00006071377,0.0008429996,0.00009765564,0.001501121],"genre_scores_gemma":[0.9861578,0.00112655,0.006571829,0.00007602107,0.00001233524,0.00005324977,0.002973395,0.00003718695,0.002991608],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001374929,"threshold_uncertainty_score":0.004599571,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04013836545499838,"score_gpt":0.2178151995295524,"score_spread":0.177676834074554,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}