{"id":"W2117992130","doi":"10.1128/iai.70.7.3673-3680.2002","title":"Strain-Dependent Induction of Enterocyte Apoptosis by<i>Giardia lamblia</i>Disrupts Epithelial Barrier Function in a Caspase-3-Dependent Manner","year":2002,"lang":"en","type":"article","venue":"Infection and Immunity","topic":"Parasitic Infections and Diagnostics","field":"Immunology and Microbiology","cited_by":231,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"Canadian Institutes of Health Research; Fondation pour la Recherche Médicale; Crohn's and Colitis Foundation of Canada; Natural Sciences and Engineering Research Council of Canada; Crohn's and Colitis Foundation","keywords":"Enterocyte; Giardia lamblia; Apoptosis; Biology; Barrier function; Tight junction; Cell biology; Caspase 3; Molecular biology; Microbiology; Biochemistry; Small intestine; Programmed cell death","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001693804,0.0002398494,0.0002356228,0.0001253829,0.0001014903,0.0002455609,0.0001387675,0.000211631,0.000704119],"category_scores_gemma":[0.0001598878,0.0001228857,0.0003096803,0.00009719572,0.0002025645,0.0001556139,0.000168066,0.0004409411,0.0002419514],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003454857,"about_ca_system_score_gemma":0.0001320187,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001188749,"about_ca_topic_score_gemma":0.001487429,"domain_scores_codex":[0.9998072,0.0000451355,0.00002482932,0.00003226252,0.00004037906,0.00005021346],"domain_scores_gemma":[0.9998956,0.00002464702,0.0000299966,0.00001979996,0.00001597034,0.00001397435],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006673117,0.00001078985,0.0001792844,0.00001699711,0.000002729309,0.00002053563,0.00000818405,0.00001058728,0.9994035,0.00001182354,0.0000108727,0.0002579909],"study_design_scores_gemma":[0.00001305145,0.0004512807,0.01627728,0.000005719532,0.00001410852,0.0002750957,0.0000474613,0.0005440939,0.9814098,0.00002522361,0.0009328981,0.000003924624],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.997363,0.0008593702,0.001028938,0.00006618338,0.00001393872,0.00001347135,0.0001329411,0.00003470109,0.0004874666],"genre_scores_gemma":[0.9969239,0.0005897361,0.001215754,0.00004763912,0.000006733655,0.00001966743,0.000376241,0.00001349084,0.0008068208],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001188749,"threshold_uncertainty_score":0.002506673,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01537366547775102,"score_gpt":0.2378031283646002,"score_spread":0.2224294628868492,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}