{"id":"W2118038884","doi":"10.1093/cvr/cvv218","title":"A novel assay uncovers an unexpected role for SR-BI in LDL transcytosis","year":2015,"lang":"en","type":"article","venue":"Cardiovascular Research","topic":"Caveolin-1 and cellular processes","field":"Biochemistry, Genetics and Molecular Biology","cited_by":171,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University; Hospital for Sick Children; University of Toronto; Toronto General Hospital; St. Michael's Hospital","funders":"Canadian Institutes of Health Research; Hospital for Sick Children; Canada Research Chairs; Fondation Leducq","keywords":"Transcytosis; Medicine; Cell biology; Internal medicine; Chemistry; Endocrinology; Biology; Endocytosis; Receptor","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003567622,0.0001840544,0.0003240685,0.000182783,0.0000858741,0.00007192986,0.0004197645,0.0002693186,0.000006408342],"category_scores_gemma":[0.0005879298,0.0001848087,0.0005127466,0.0004832939,0.0001355674,0.00001387154,0.0001070885,0.0002408628,0.00001170608],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007865924,"about_ca_system_score_gemma":0.0003752944,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002780606,"about_ca_topic_score_gemma":0.0001799915,"domain_scores_codex":[0.9974513,0.0002986754,0.0002180391,0.0006791943,0.0007272511,0.0006255105],"domain_scores_gemma":[0.9981605,0.00003547454,0.0000210306,0.0008434455,0.0006550389,0.000284478],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006529539,0.0003891967,0.0008644535,0.0001250848,0.0007737206,0.00002985489,0.0007327503,0.00286,0.9712441,0.0001052957,0.001146931,0.02107567],"study_design_scores_gemma":[0.005564148,0.0007914465,0.000443894,0.00003727307,0.00009114745,0.00005935108,0.002857378,0.0005630651,0.6453866,0.0003888678,0.3432959,0.0005209135],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9349686,0.02219771,0.03811431,0.0001049667,0.0001535768,0.001046571,0.00007192884,0.00003385911,0.003308462],"genre_scores_gemma":[0.9975638,0.0003716348,0.0005377854,0.0000306786,0.0003973376,0.0002703593,0.000293847,0.00005652159,0.0004780766],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.342149,"threshold_uncertainty_score":0.7536279,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08377290347679488,"score_gpt":0.3421420482313084,"score_spread":0.2583691447545136,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}