{"id":"W2118123309","doi":"10.1186/1744-8069-1-22","title":"Genetic Alteration of Anxiety and Stress-Like Behavior in Mice Lacking CaMKIV","year":2005,"lang":"en","type":"article","venue":"Molecular Pain","topic":"Neuroendocrine regulation and behavior","field":"Psychology","cited_by":35,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"Canadian Institutes of Health Research","keywords":"Prepulse inhibition; CREB; Startle response; Anxiety; Knockout mouse; Protein kinase A; CREB-binding protein; Neuroscience; Transcription factor; Psychology; Endocrinology; Biology; Internal medicine; Phosphorylation; Cell biology; Medicine; Gene; Genetics; Psychiatry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001737617,0.001050659,0.0003952003,0.001040559,0.0002555151,0.0004715538,0.0005756234,0.0008078395,0.002625439],"category_scores_gemma":[0.0002448131,0.0004820666,0.0004534631,0.0002729336,0.0007404989,0.0003171615,0.0003619149,0.001294188,0.0005247631],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004752629,"about_ca_system_score_gemma":0.0002721704,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009906065,"about_ca_topic_score_gemma":0.001567678,"domain_scores_codex":[0.99976,0.00003063079,0.00003492312,0.00006361087,0.00005001724,0.00006085284],"domain_scores_gemma":[0.9994934,0.00005235314,0.0002351334,0.00003332999,0.00002292374,0.0001629615],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001800463,0.00005788582,0.0001786851,0.00002338799,0.000009082384,0.0001136951,0.00001736936,0.00005570728,0.9986439,0.0001587646,0.00003794569,0.0005235811],"study_design_scores_gemma":[0.0003476548,0.001244534,0.02041471,0.00007006126,0.0001290697,0.002114891,0.0001621224,0.003059088,0.9694797,0.0003865228,0.002550559,0.00004118748],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9944751,0.0005716562,0.00274513,0.0001660975,0.0000537976,0.00004446608,0.0008812228,0.0002505473,0.0008119292],"genre_scores_gemma":[0.989059,0.0007748311,0.004148355,0.0001384244,0.00003118186,0.0001208529,0.001134739,0.0001559104,0.004436786],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002625439,"threshold_uncertainty_score":0.008782983,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01271956248651223,"score_gpt":0.2939606337673059,"score_spread":0.2812410712807936,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}