{"id":"W2118125186","doi":"10.4049/jimmunol.1202861","title":"Comparative Analysis of the Magnitude, Quality, Phenotype, and Protective Capacity of Simian Immunodeficiency Virus Gag-Specific CD8+ T Cells following Human-, Simian-, and Chimpanzee-Derived Recombinant Adenoviral Vector Immunization","year":2013,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":110,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Infection and Immunity","funders":"National Institute of Allergy and Infectious Diseases; National Institutes of Health; Wellcome Trust","keywords":"Biology; CD8; Simian immunodeficiency virus; Virology; Cytotoxic T cell; T cell; Priming (agriculture); Viral vector; Immunology; Virus; Recombinant DNA; Immune system; Genetics; In vitro; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001062996,0.000196229,0.0006015368,0.0001949872,0.0002593991,0.0000226538,0.0005665977,0.000146058,0.00003728711],"category_scores_gemma":[0.00009135062,0.0001246597,0.0002171629,0.0004663513,0.0008605174,0.00002377848,0.0002690428,0.0003973546,0.000001103269],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003879964,"about_ca_system_score_gemma":0.00008965766,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005307129,"about_ca_topic_score_gemma":0.0002238347,"domain_scores_codex":[0.9973057,0.001332665,0.0006868173,0.0001799269,0.0002416888,0.000253224],"domain_scores_gemma":[0.9979831,0.0001205359,0.0008675431,0.0005010567,0.0004925466,0.00003519137],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0008681168,0.0001794795,0.0006002559,0.00001198828,0.00158688,3.56523e-7,0.002661017,0.0002239416,0.9934169,0.00003419503,0.00001001331,0.0004068306],"study_design_scores_gemma":[0.001094557,0.003035557,0.1156038,0.00002740513,0.0002766283,0.000009073983,0.001843375,0.00006377987,0.8776594,0.0002238552,0.00001934579,0.0001432162],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9937563,0.005225303,0.0002077204,0.0001553602,0.0001163417,0.0004758109,0.00001434403,0.000002550035,0.00004630417],"genre_scores_gemma":[0.9988869,0.0009281858,0.00008497849,0.00002483528,0.00001970576,0.000007776541,0.000005837635,0.00001437065,0.00002738437],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1157575,"threshold_uncertainty_score":0.5083476,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03302498094918928,"score_gpt":0.3031531900516495,"score_spread":0.2701282091024602,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}