{"id":"W2118125186","doi":"10.4049/jimmunol.1202861","title":"Comparative Analysis of the Magnitude, Quality, Phenotype, and Protective Capacity of Simian Immunodeficiency Virus Gag-Specific CD8+ T Cells following Human-, Simian-, and Chimpanzee-Derived Recombinant Adenoviral Vector Immunization","year":2013,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":110,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Infection and Immunity","funders":"National Institute of Allergy and Infectious Diseases; National Institutes of Health; Wellcome Trust","keywords":"Biology; CD8; Simian immunodeficiency virus; Virology; Cytotoxic T cell; T cell; Priming (agriculture); Viral vector; Immunology; Virus; Recombinant DNA; Immune system; Genetics; In vitro; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002580052,0.0001860935,0.000168292,0.0001813666,0.00005867446,0.0002002972,0.00007117887,0.0001902924,0.0006406549],"category_scores_gemma":[0.0002579142,0.00009867451,0.0001202845,0.00008921882,0.0001454323,0.0001769956,0.00009840859,0.0003137118,0.0001580358],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007581463,"about_ca_system_score_gemma":0.00003863988,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001005035,"about_ca_topic_score_gemma":0.0001409746,"domain_scores_codex":[0.9998775,0.0000247954,0.00001232645,0.00003135518,0.00002416866,0.00002991746],"domain_scores_gemma":[0.9998285,0.00005008998,0.00002724636,0.00002054775,0.00003035716,0.00004322789],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002365606,0.00004208287,0.001963613,0.00002683715,0.000008441172,0.0000179513,0.00004349104,0.0001058684,0.9951414,0.00003335601,0.00001479889,0.002365614],"study_design_scores_gemma":[0.0001130934,0.01058469,0.1399057,0.00002012948,0.0001237047,0.001000715,0.0002209169,0.002455644,0.8430816,0.0002262553,0.002251229,0.00001638774],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.998871,0.0002757137,0.000353334,0.000007662973,0.00000234909,0.00001132019,0.0000831871,0.000008964975,0.0003863764],"genre_scores_gemma":[0.9985078,0.0001756712,0.0005360213,0.00002169824,0.000004228082,0.00002008176,0.0003052617,0.000004738109,0.0004243803],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0006406549,"threshold_uncertainty_score":0.002143204,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03302498094918928,"score_gpt":0.3031531900516495,"score_spread":0.2701282091024602,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}