{"id":"W2118165374","doi":"10.1111/j.1601-183x.2011.00719.x","title":"rKv1.2 overexpression in the central medial thalamic area decreases caffeine-induced arousal","year":2011,"lang":"en","type":"article","venue":"Genes Brain & Behavior","topic":"Ion channel regulation and function","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"Discovery Centre","funders":"University of Pennsylvania","keywords":"Sleep (system call); Potassium channel; Arousal; Caffeine; In vivo; Electrophysiology; Endocrinology; Neuroscience; Inhibitory postsynaptic potential; Internal medicine; In situ hybridization; Adeno-associated virus; Biology; Vector (molecular biology); Chemistry; Medicine; Biochemistry; Gene; Gene expression; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001500081,0.0001572318,0.0001013314,0.00005085439,0.00008134828,0.00001756259,0.0001915867,0.000178241,0.0001443959],"category_scores_gemma":[0.00007631076,0.0001162203,0.00008707229,0.00008493926,0.0000425559,0.000007217086,0.00005295746,0.0000790621,0.00001015866],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001637285,"about_ca_system_score_gemma":0.00005457766,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001342806,"about_ca_topic_score_gemma":0.0001100861,"domain_scores_codex":[0.998957,0.0001200925,0.0001841941,0.0002851332,0.0001739744,0.0002795449],"domain_scores_gemma":[0.9995162,0.00002170124,0.00006251127,0.0002909306,0.00003659073,0.00007210042],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001278897,0.0002152071,0.02153249,0.000003238406,0.000005213621,0.00001572692,0.0005507527,0.000007299844,0.9703944,0.0000322141,0.001788391,0.005327155],"study_design_scores_gemma":[0.001058802,0.0002952948,0.3712741,0.0000273646,0.00002660708,0.00005581675,0.0006662976,0.00006688998,0.6222294,0.00002950686,0.003992948,0.000276947],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9985481,0.0001057464,0.0001414684,0.00009805197,0.0004677115,0.0002913254,0.00001226095,0.00001757697,0.0003177891],"genre_scores_gemma":[0.9983699,0.00002745734,0.0001104583,0.0003498856,0.0005602414,0.00009462976,0.0002450455,0.00001910885,0.0002233217],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3497416,"threshold_uncertainty_score":0.4739327,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04237470237631205,"score_gpt":0.2655532420067308,"score_spread":0.2231785396304188,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}