{"id":"W2118187336","doi":"10.4049/jimmunol.1300093","title":"CD40 Ligand Preferentially Modulates Immune Response and Enhances Protection against Influenza Virus","year":2014,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"Immunotherapy and Immune Responses","field":"Immunology and Microbiology","cited_by":40,"is_retracted":false,"has_abstract":true,"ca_institutions":"Public Health Agency of Canada; University of Ottawa; Health Canada","funders":"","keywords":"Germinal center; Immune system; Adjuvant; Biology; Virology; CD40; CTL*; Virus; Immunization; Immunology; Influenza A virus; T cell; CD8; Cytotoxic T cell; B cell; Antibody; In vitro; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002836073,0.0002748826,0.0005551403,0.0002892188,0.0004752412,0.00003642546,0.0005387291,0.0003415509,0.00008593113],"category_scores_gemma":[0.0005627532,0.0001769597,0.0001477667,0.0001612062,0.0007375898,0.0002621004,0.0001372918,0.0008380245,0.00008551209],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004202897,"about_ca_system_score_gemma":0.0001106385,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00007754124,"about_ca_topic_score_gemma":0.000009175994,"domain_scores_codex":[0.9956635,0.00284662,0.0008642615,0.0001603928,0.00006570053,0.0003995799],"domain_scores_gemma":[0.9976341,0.0008638864,0.0008292842,0.0004264588,0.0002290727,0.00001715555],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.02467628,0.00009782973,0.00002609109,0.000009063643,0.0006830718,0.000001326459,0.001404309,0.00002211799,0.9481249,0.00008101486,0.0000639561,0.02481],"study_design_scores_gemma":[0.002769882,0.002352235,0.02519198,0.0001077853,0.00009318496,0.0006990682,0.0004881185,0.000006427463,0.9308543,0.0003354062,0.03690283,0.000198815],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9546153,0.04265789,0.0007275869,0.0006045752,0.001039973,0.0002336414,0.000003243251,0.00003259188,0.00008522274],"genre_scores_gemma":[0.9944462,0.004440111,0.00003941229,0.0002568141,0.00005419796,0.000008727609,0.000002392979,0.0000276398,0.0007244932],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03983093,"threshold_uncertainty_score":0.7216206,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01302573180037144,"score_gpt":0.238580387554257,"score_spread":0.2255546557538856,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}