{"id":"W2118222343","doi":"10.2147/ijn.s54050","title":"Improving aqueous solubility and antitumor effects by nanosized gambogic acid-mPEG2000 micelles","year":2013,"lang":"en","type":"article","venue":"International Journal of Nanomedicine","topic":"Natural Compound Pharmacology Studies","field":"Agricultural and Biological Sciences","cited_by":43,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal","funders":"National Natural Science Foundation of China; University of Nebraska Medical Center","keywords":"Gambogic acid; Micelle; Aqueous solution; Solubility; Materials science; Bioavailability; Chemical engineering; Nanotechnology; Chemistry; Organic chemistry; Pharmacology; Biochemistry; In vitro; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001255331,0.0003311495,0.0001323597,0.0001673573,0.00005387415,0.0001292205,0.0001320851,0.0002002361,0.0003470947],"category_scores_gemma":[0.0001058128,0.00008000022,0.00009144419,0.00007373316,0.0001271543,0.0001890745,0.0001259389,0.0002248001,0.0001338636],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001598593,"about_ca_system_score_gemma":0.0001446511,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003418754,"about_ca_topic_score_gemma":0.0004077035,"domain_scores_codex":[0.9999619,0.000008350925,0.000002992243,0.000007398933,0.00001113214,0.000008271679],"domain_scores_gemma":[0.9999703,0.000005315263,0.0000106847,0.000001745806,0.000005858572,0.000006065087],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003102992,0.00001401301,0.00003327374,0.00002169742,0.000001821925,0.00001339689,0.000004456102,0.000065149,0.9985529,0.00005336423,0.0000122528,0.001196651],"study_design_scores_gemma":[0.00001649251,0.000264405,0.0003419855,0.000003935994,0.00001003102,0.00006536429,0.000002995115,0.0009388575,0.9971173,0.00001732779,0.001219571,0.000001875189],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9903609,0.002642184,0.005778941,0.00009149465,0.00001811265,0.00004779024,0.00004405844,0.00007491085,0.0009417784],"genre_scores_gemma":[0.9907963,0.001341692,0.00627243,0.00004547648,0.00001177323,0.00003186435,0.00008805787,0.00001354661,0.001398776],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0003470947,"threshold_uncertainty_score":0.001161218,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00449198993242758,"score_gpt":0.2215942101151097,"score_spread":0.2171022201826821,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}