{"id":"W2118279581","doi":"10.1152/ajpheart.2001.281.3.h1334","title":"Inhibition of Na<sup>+</sup>/Ca<sup>2+</sup> exchange by KB-R7943: transport mode selectivity and antiarrhythmic consequences","year":2001,"lang":"en","type":"article","venue":"American Journal of Physiology-Heart and Circulatory Physiology","topic":"Cardiac electrophysiology and arrhythmias","field":"Medicine","cited_by":106,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba; Hospital for Sick Children; St. Boniface Hospital","funders":"","keywords":"Sodium-calcium exchanger; Chemistry; Patch clamp; Biophysics; Ion transporter; Ischemia; Intracellular; Membrane potential; Myocyte; Internal medicine; Cardiology; Biochemistry; Membrane; Medicine; Biology; Receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","sts"],"consensus_categories":[],"category_scores_codex":[0.0003728498,0.0004655279,0.001938931,0.000288172,0.0002145917,0.000005937874,0.0001018083,0.0002889751,0.0001132668],"category_scores_gemma":[0.00005049176,0.0004031275,0.0004245813,0.0004275147,0.0031514,0.0002559397,0.00004527928,0.0008321058,0.000007579309],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006289568,"about_ca_system_score_gemma":0.0002803344,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001659117,"about_ca_topic_score_gemma":0.000002279277,"domain_scores_codex":[0.9970555,0.0005546433,0.0007926876,0.0006864897,0.0002415446,0.0006691694],"domain_scores_gemma":[0.9981545,0.0002487334,0.0006234979,0.0003613624,0.0002942295,0.0003176965],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.001497087,0.0002184328,0.003538007,0.0001318754,0.0004586536,0.000028492,0.0009377638,0.001305214,0.9902586,0.0000398207,0.000622139,0.0009639314],"study_design_scores_gemma":[0.005706782,0.01010091,0.9318839,0.0003678097,0.0009429671,0.01195229,0.00224689,0.004585271,0.02556939,0.003986416,0.00153391,0.001123503],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9968057,0.002036118,0.000019757,0.0006179122,0.00008275211,0.0002948636,0.0000533873,0.00003282504,0.0000566685],"genre_scores_gemma":[0.9957705,0.001881629,0.0001208761,0.001536049,0.0005579601,0.00001632043,0.00005120673,0.00004150191,0.0000239706],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.9646892,"threshold_uncertainty_score":0.999842,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008555642874168823,"score_gpt":0.2443029245668719,"score_spread":0.2357472816927031,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}