{"id":"W2118279581","doi":"10.1152/ajpheart.2001.281.3.h1334","title":"Inhibition of Na<sup>+</sup>/Ca<sup>2+</sup> exchange by KB-R7943: transport mode selectivity and antiarrhythmic consequences","year":2001,"lang":"en","type":"article","venue":"American Journal of Physiology-Heart and Circulatory Physiology","topic":"Cardiac electrophysiology and arrhythmias","field":"Medicine","cited_by":106,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba; Hospital for Sick Children; St. Boniface Hospital","funders":"","keywords":"Sodium-calcium exchanger; Chemistry; Patch clamp; Biophysics; Ion transporter; Ischemia; Intracellular; Membrane potential; Myocyte; Internal medicine; Cardiology; Biochemistry; Membrane; Medicine; Biology; Receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002932719,0.0004002931,0.0006479769,0.0001163456,0.0001374391,0.0002717193,0.0003643463,0.000307913,0.0008986039],"category_scores_gemma":[0.0001787759,0.0001501307,0.0002810045,0.0001370196,0.000245516,0.0003385273,0.0001687435,0.0005619809,0.0003016718],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001683114,"about_ca_system_score_gemma":0.0002189177,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004782483,"about_ca_topic_score_gemma":0.0007229284,"domain_scores_codex":[0.9998558,0.00002207849,0.00002237435,0.0000240263,0.00003123179,0.0000444755],"domain_scores_gemma":[0.9999058,0.00002636266,0.00002606724,0.000009756047,0.00001229514,0.00001962901],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002201266,0.00003231441,0.0001152398,0.0000590381,0.00001013867,0.00007269474,0.00001424441,0.00003800799,0.9981451,0.00005293015,0.00002313845,0.001216975],"study_design_scores_gemma":[0.0001123548,0.001170182,0.007720343,0.00001044301,0.00006127867,0.0006105814,0.00003665781,0.0009769852,0.9879599,0.00003725625,0.00129409,0.00001000755],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9935056,0.00426973,0.000775855,0.00008234917,0.00002559385,0.00003183694,0.0001389398,0.00003945873,0.001130569],"genre_scores_gemma":[0.9951023,0.002600831,0.001098862,0.00007464508,0.00002243818,0.00003460318,0.0002487348,0.00001949247,0.0007980885],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008986039,"threshold_uncertainty_score":0.003006101,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008555642874168823,"score_gpt":0.2443029245668719,"score_spread":0.2357472816927031,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}