{"id":"W2118290322","doi":"10.1002/path.2636","title":"Does massively parallel DNA resequencing signify the end of histopathology as we know it?","year":2009,"lang":"en","type":"review","venue":"The Journal of Pathology","topic":"Cancer Genomics and Diagnostics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":55,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia; BC Cancer Agency","funders":"","keywords":"Massive parallel sequencing; DNA sequencing; Genome; Genomics; Biology; Computational biology; Cancer; Personal genomics; Genetics; DNA; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002167731,0.0007579449,0.001843828,0.002114695,0.0003132985,0.001473023,0.001337869,0.002193321,0.003643988],"category_scores_gemma":[0.003696072,0.0003532021,0.0004122269,0.001557832,0.001430396,0.003243055,0.0005997539,0.002628226,0.005026086],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00096131,"about_ca_system_score_gemma":0.00102485,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009013647,"about_ca_topic_score_gemma":0.001592416,"domain_scores_codex":[0.9995061,0.0001092683,0.00006407193,0.00007642415,0.0002110859,0.0000329953],"domain_scores_gemma":[0.9981331,0.001013608,0.0001594947,0.00007699862,0.0004834937,0.0001333905],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0000919122,0.00004107793,0.0001537787,0.004987006,0.00005141195,0.0003252462,0.00004256935,0.0002564229,0.001286076,0.005407351,0.04817433,0.9391829],"study_design_scores_gemma":[0.00002976278,0.00009300953,0.0006902755,0.002760838,0.00004492635,0.0028238,0.0001005029,0.0001121728,0.0009506511,0.006329822,0.9860343,0.00003001103],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001147775,0.9945846,0.0005146388,0.002299474,0.001081479,0.000004947477,0.00001289227,0.0000240272,0.001363169],"genre_scores_gemma":[0.0009714731,0.9953735,0.0007009617,0.001099166,0.0006496883,0.000008447579,0.00001909654,0.000004847813,0.001172848],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003643988,"threshold_uncertainty_score":0.01219034,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02755886785958452,"score_gpt":0.3142282678531708,"score_spread":0.2866693999935863,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}