{"id":"W2118362648","doi":"10.1186/1471-2474-14-27","title":"Subchondral pre-solidified chitosan/blood implants elicit reproducible early osteochondral wound-repair responses including neutrophil and stromal cell chemotaxis, bone resorption and repair, enhanced repair tissue integration and delayed matrix deposition","year":2013,"lang":"en","type":"article","venue":"BMC Musculoskeletal Disorders","topic":"Osteoarthritis Treatment and Mechanisms","field":"Medicine","cited_by":36,"is_retracted":false,"has_abstract":true,"ca_institutions":"Dalhousie University; McGill University Health Centre; Montreal General Hospital; Piramal (Canada); Polytechnique Montréal","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; Canadian Arthritis Network; Fonds Québécois de la Recherche sur la Nature et les Technologies","keywords":"Stromal cell; Medicine; Resorption; Bone marrow; Bone resorption; Pathology; Implant; Demineralized bone matrix; Cartilage; Bone remodeling; Chitosan; Biomedical engineering; Anatomy; Surgery; Materials science; Chemistry; Internal medicine; dBm","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002462359,0.0005495062,0.0002708898,0.0002786913,0.00008065631,0.0003061643,0.000148764,0.0002998027,0.0008025014],"category_scores_gemma":[0.0002400512,0.0001915571,0.0002073654,0.0001296483,0.0003070403,0.0002367377,0.0001536211,0.0003335006,0.0002018271],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002853174,"about_ca_system_score_gemma":0.0002351616,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007011457,"about_ca_topic_score_gemma":0.001451749,"domain_scores_codex":[0.9998111,0.00001312397,0.00002670612,0.00004535405,0.00006545262,0.00003827507],"domain_scores_gemma":[0.9996325,0.0000383342,0.0001859613,0.00003347448,0.00004861919,0.00006105993],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008112349,0.0000205965,0.0001267895,0.00001909599,0.000002065843,0.00002134894,0.000008451021,0.00001475642,0.9990969,0.000008474869,0.000004269002,0.0005962642],"study_design_scores_gemma":[0.00001993047,0.002026192,0.004201834,0.000005791177,0.00002771221,0.0001837203,0.00002407855,0.0002002687,0.9926652,0.00001003886,0.0006301801,0.000005034879],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9961932,0.0008637313,0.002434612,0.00002118927,0.00001832168,0.00003721465,0.00007629551,0.00004346222,0.0003119979],"genre_scores_gemma":[0.9939315,0.0005961246,0.003886885,0.00003240793,0.00001365092,0.00003932467,0.0001673374,0.00001627892,0.001316444],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008025014,"threshold_uncertainty_score":0.002684593,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009666944134519554,"score_gpt":0.2646484702838636,"score_spread":0.254981526149344,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}